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- W2979382080 abstract "Hydroxychloroquine is an antimalarial agent with immunosuppressive and cytotoxic properties that is considered safe and effective in pregnant patients with a history of mild lupus nephritis (LN). 1 Lech M. Anders H. The pathogenesis of lupus nephritis. J Am Soc Nephrol. 2013; 24: 1357-1366 Crossref PubMed Scopus (280) Google Scholar ,2 Hahn B.H. McMahon M.A. Wilkinson A. et al. American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis. Arthritis Care Res. 2012; 64: 797-808 Crossref PubMed Scopus (946) Google Scholar Hypersensitivity to hydroxychloroquine usually manifests as maculopapular exanthems within 2 to 33 days and rarely as eosinophilia or other systemic symptoms. 3 Barailler H. Milpied B. Chauvel A. et al. Delayed hypersensitivity skin reaction to hydroxychloroquine: successful short desensitization. J Allergy Clin Immunol Pract. 2019; 7: 307-308 Abstract Full Text Full Text PDF PubMed Scopus (7) Google Scholar Several prolonged desensitization protocols, ranging from 4 to 36 days, have been proposed to manage prior histories of hydroxychloroquine hypersensitivity. 3 Barailler H. Milpied B. Chauvel A. et al. Delayed hypersensitivity skin reaction to hydroxychloroquine: successful short desensitization. J Allergy Clin Immunol Pract. 2019; 7: 307-308 Abstract Full Text Full Text PDF PubMed Scopus (7) Google Scholar , 4 Mates M. Zevin S. Breuer G.S. et al. Desensitization to hydroxychloroquine: experience of 4 patients. J Rheumatol. 2006; 33: 814-816 Google Scholar , 5 Caramaschi P. Desensitization to hydroxychloroquine: 4 cases. J Rheumatol. 2011; 38: 2267 Crossref PubMed Scopus (6) Google Scholar , 6 Tal Y. Maoz S. Langevitz P. et al. Hydroxychloroquine desensitization, an effective method to overcome hypersensitivity: a multicenter experience. Lupus. 2018; 27: 703-707 Crossref PubMed Scopus (11) Google Scholar , 7 Donado C.D. Díez E.M. Successful desensitization for hydroxychloroquine anaphylaxis. J Rheumatol. 2010; 37: 1975-1976 Google Scholar We report the first successful rapid desensitization to hydroxychloroquine in a female patient of reproductive age with a history of LN and hypersensitivity to hydroxychloroquine." @default.
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- W2979382080 date "2020-01-01" @default.
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- W2979382080 title "Rapid desensitization of hydroxychloroquine" @default.
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- W2979382080 doi "https://doi.org/10.1016/j.anai.2019.10.001" @default.
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