Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979419625> ?p ?o ?g. }
- W2979419625 endingPage "108265" @default.
- W2979419625 startingPage "108265" @default.
- W2979419625 abstract "Developing an ideal wound dressing material which could accelerate wound closure and achieve scarless wound healing was the ultimate goal of numerous researchers. In this study, biomimetic silk fibroin (SF)/polycaprolactone (PCL) matrices were fabricated via co-electrospinning and positively charged chitosan (CS) and negatively charged type I collagen (COL) were deposited on the nanofibrous mats through electrostatic layer-by-layer (LBL) self-assembly technique. Scanning electron microscopy images indicate that the average fiber diameter of SF/PCL nanofibers became larger and more and more irregular protuberances were observed on their surfaces with the LBL process. Besides, the chemical structure and composition investigation further verified the successful deposition of CS/COL. Additionally, tensile strength and water contact angle tests showed the LBL modified mats had enhanced mechanical properties and good hydrophilicity. Moreover, LBL structured mats acquired excellent antibacterial activity and better ability to promote cell attachment, growth and proliferation. Ultimately, in vivo wound healing assay in rat models revealed that LBL structured mats could reduce the wound closure time, increase collagen production and mitigate excessive scar formation through TGF-β/Smad signaling pathways, which demonstrated the potential application of the nanofibrous mats in skin regeneration." @default.
- W2979419625 created "2019-10-18" @default.
- W2979419625 creator A5008154260 @default.
- W2979419625 creator A5044521029 @default.
- W2979419625 creator A5054836556 @default.
- W2979419625 creator A5057652307 @default.
- W2979419625 creator A5060793406 @default.
- W2979419625 creator A5066109863 @default.
- W2979419625 date "2020-01-01" @default.
- W2979419625 modified "2023-10-16" @default.
- W2979419625 title "Accelerating dermal wound healing and mitigating excessive scar formation using LBL modified nanofibrous mats" @default.
- W2979419625 cites W1742240530 @default.
- W2979419625 cites W1964794578 @default.
- W2979419625 cites W1981605170 @default.
- W2979419625 cites W1988721141 @default.
- W2979419625 cites W1989785013 @default.
- W2979419625 cites W1989804649 @default.
- W2979419625 cites W1990589377 @default.
- W2979419625 cites W1999878829 @default.
- W2979419625 cites W2000476211 @default.
- W2979419625 cites W2001157537 @default.
- W2979419625 cites W2003832670 @default.
- W2979419625 cites W2004107815 @default.
- W2979419625 cites W2014011572 @default.
- W2979419625 cites W2014778384 @default.
- W2979419625 cites W2016349955 @default.
- W2979419625 cites W2026547102 @default.
- W2979419625 cites W2057468212 @default.
- W2979419625 cites W2062066001 @default.
- W2979419625 cites W2063060543 @default.
- W2979419625 cites W2064583455 @default.
- W2979419625 cites W2068933459 @default.
- W2979419625 cites W2069527786 @default.
- W2979419625 cites W2082387225 @default.
- W2979419625 cites W2107524547 @default.
- W2979419625 cites W2129286943 @default.
- W2979419625 cites W2184184250 @default.
- W2979419625 cites W2289752352 @default.
- W2979419625 cites W2331202848 @default.
- W2979419625 cites W2395077953 @default.
- W2979419625 cites W2471355668 @default.
- W2979419625 cites W2513022280 @default.
- W2979419625 cites W2579920203 @default.
- W2979419625 cites W2594281910 @default.
- W2979419625 cites W2734691708 @default.
- W2979419625 cites W2740360794 @default.
- W2979419625 cites W2756797184 @default.
- W2979419625 cites W2766283572 @default.
- W2979419625 cites W2782428150 @default.
- W2979419625 cites W2783749957 @default.
- W2979419625 cites W2794778904 @default.
- W2979419625 cites W2898220581 @default.
- W2979419625 cites W2945349435 @default.
- W2979419625 cites W2079955905 @default.
- W2979419625 doi "https://doi.org/10.1016/j.matdes.2019.108265" @default.
- W2979419625 hasPublicationYear "2020" @default.
- W2979419625 type Work @default.
- W2979419625 sameAs 2979419625 @default.
- W2979419625 citedByCount "61" @default.
- W2979419625 countsByYear W29794196252020 @default.
- W2979419625 countsByYear W29794196252021 @default.
- W2979419625 countsByYear W29794196252022 @default.
- W2979419625 countsByYear W29794196252023 @default.
- W2979419625 crossrefType "journal-article" @default.
- W2979419625 hasAuthorship W2979419625A5008154260 @default.
- W2979419625 hasAuthorship W2979419625A5044521029 @default.
- W2979419625 hasAuthorship W2979419625A5054836556 @default.
- W2979419625 hasAuthorship W2979419625A5057652307 @default.
- W2979419625 hasAuthorship W2979419625A5060793406 @default.
- W2979419625 hasAuthorship W2979419625A5066109863 @default.
- W2979419625 hasBestOaLocation W29794196251 @default.
- W2979419625 hasConcept C112950240 @default.
- W2979419625 hasConcept C122302759 @default.
- W2979419625 hasConcept C127413603 @default.
- W2979419625 hasConcept C136229726 @default.
- W2979419625 hasConcept C141071460 @default.
- W2979419625 hasConcept C144796933 @default.
- W2979419625 hasConcept C159985019 @default.
- W2979419625 hasConcept C171250308 @default.
- W2979419625 hasConcept C192562407 @default.
- W2979419625 hasConcept C2777538232 @default.
- W2979419625 hasConcept C2779732960 @default.
- W2979419625 hasConcept C2779868350 @default.
- W2979419625 hasConcept C2780269544 @default.
- W2979419625 hasConcept C2780431358 @default.
- W2979419625 hasConcept C2993269979 @default.
- W2979419625 hasConcept C42360764 @default.
- W2979419625 hasConcept C521977710 @default.
- W2979419625 hasConcept C71924100 @default.
- W2979419625 hasConcept C91129048 @default.
- W2979419625 hasConceptScore W2979419625C112950240 @default.
- W2979419625 hasConceptScore W2979419625C122302759 @default.
- W2979419625 hasConceptScore W2979419625C127413603 @default.
- W2979419625 hasConceptScore W2979419625C136229726 @default.
- W2979419625 hasConceptScore W2979419625C141071460 @default.
- W2979419625 hasConceptScore W2979419625C144796933 @default.
- W2979419625 hasConceptScore W2979419625C159985019 @default.
- W2979419625 hasConceptScore W2979419625C171250308 @default.