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• W2979423594 endingPage "134500" @default.
• W2979423594 startingPage "134500" @default.
• W2979423594 abstract "Flumethrin is a typical pyrethroid varroacide widely used for mite control in beekeeping worldwide. Currently, information on the toxicological characteristics of flumethrin on bees at sublethal concentrations is still lacking. To fill this gap in information, we performed a 48-h acute oral and 14-day chronic toxicity testing of flumethrin in newly emerged adult honey bees under laboratory conditions. Results showed that flumethrin had high acute toxicity to honey bees with a 48-h LD50 of 0.47 µg/bee (95% CI, 0.39 ∼ 0.57 µg/bee), which is higher than that of many other commercial pyrethroid insecticides, but lower than that of tau-fluvalinate. After 14 days of chronic exposure to flumethrin at 0.01, 0.10, and 1.0 mg/L, significant antioxidant response, detoxification, immune reaction, and apoptosis were observed in the midguts. These findings indicated that flumethrin had potential risks to bees, and it can disturb the homeostasis of bees at sublethal concentrations under longer exposure conditions. Flumethrin is highly lipophilic and easy to accumulate in beeswax; thus, careless practices might pose risks to colony development in commercial beekeeping and native populations. This laboratory study can serve as an early warning, and further studies are required to understand the real residual level of flumethrin in bees and the risks of flumethrin in field condition." @default.
• W2979423594 created "2019-10-18" @default.
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• W2979423594 date "2020-01-01" @default.
• W2979423594 modified "2023-10-16" @default.
• W2979423594 title "Flumethrin at sublethal concentrations induces stresses in adult honey bees (Apis mellifera L.)" @default.
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• W2979423594 doi "https://doi.org/10.1016/j.scitotenv.2019.134500" @default.
• W2979423594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31627045" @default.
• W2979423594 hasPublicationYear "2020" @default.
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