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- W2979426601 endingPage "1225" @default.
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- W2979426601 abstract "Cancer development, growth, and metastasis are highly regulated by several transcription regulators (TRs), namely transcription factors, oncogenes, tumor-suppressor genes, and protein kinases. Although TR roles in these events have been well characterized, their functions in regulating other important cancer cell processes, such as metabolism, have not been systematically examined. In this review, we describe, analyze, and strive to reconstruct the regulatory networks of several TRs acting in the energy metabolism pathways, glycolysis (and its main branching reactions), and oxidative phosphorylation of nonmetastatic and metastatic cancer cells. Moreover, we propose which possible gene targets might allow these TRs to facilitate the modulation of each energy metabolism pathway, depending on the tumor microenvironment." @default.
- W2979426601 created "2019-10-18" @default.
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- W2979426601 date "2019-10-09" @default.
- W2979426601 modified "2023-10-18" @default.
- W2979426601 title "Transcriptional Regulation of Energy Metabolism in Cancer Cells" @default.
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