FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979452641> ?p ?o ?g. }

• W2979452641 endingPage "vi137" @default.
• W2979452641 startingPage "vi137" @default.
• W2979452641 abstract "Abstract Background Mismatch repair deficiency (dMMR) / microsatellite instability-high (MSI-H) in cells lead to neoplastic development and progression, an important feature in Lynch syndrome. dMMR/MSI-H is a positive predictive marker for immune checkpoint inhibitors. Nivolumab is a PD-1 inhibitor, approved in the US for pts with dMMR/MSI-H colorectal cancers. Other than colorectal cancers, a subset of rare cancers also share this characteristic. Methods This is a phase 2, open-label, single arm study designed to investigate the efficacy and safety of nivolumab monotherapy in patients with advanced rare tumors with dMMR/MSI-H. This study is conducted as part of the MASTER KEY Project, which is a basket/umbrella trial including a registry study for rare cancers (UMI27552). dMMR was identified by a negative immunohistochemical staining of one of the following: MLH1, MSH2, MSH6, PMS2. Rare cancer was defined as annual incidence Clinical Trial Information JMA-IIA00344" @default.
• W2979452641 created "2019-10-18" @default.
• W2979452641 creator A5005598571 @default.
• W2979452641 creator A5015679349 @default.
• W2979452641 creator A5021522674 @default.
• W2979452641 creator A5022390433 @default.
• W2979452641 creator A5022854492 @default.
• W2979452641 creator A5039879533 @default.
• W2979452641 creator A5059834800 @default.
• W2979452641 creator A5077644323 @default.
• W2979452641 creator A5078675059 @default.
• W2979452641 creator A5079777926 @default.
• W2979452641 creator A5085617402 @default.
• W2979452641 date "2019-10-01" @default.
• W2979452641 modified "2023-10-12" @default.
• W2979452641 title "ROCK Trial (NCCH1709): Nivolumab monotherapy in Rare cancer patients with mismatch repair deficiency biomarker: phase II" @default.
• W2979452641 doi "https://doi.org/10.1093/annonc/mdz343.088" @default.
• W2979452641 hasPublicationYear "2019" @default.
• W2979452641 type Work @default.
• W2979452641 sameAs 2979452641 @default.
• W2979452641 citedByCount "0" @default.
• W2979452641 crossrefType "journal-article" @default.
• W2979452641 hasAuthorship W2979452641A5005598571 @default.
• W2979452641 hasAuthorship W2979452641A5015679349 @default.
• W2979452641 hasAuthorship W2979452641A5021522674 @default.
• W2979452641 hasAuthorship W2979452641A5022390433 @default.
• W2979452641 hasAuthorship W2979452641A5022854492 @default.
• W2979452641 hasAuthorship W2979452641A5039879533 @default.
• W2979452641 hasAuthorship W2979452641A5059834800 @default.
• W2979452641 hasAuthorship W2979452641A5077644323 @default.
• W2979452641 hasAuthorship W2979452641A5078675059 @default.
• W2979452641 hasAuthorship W2979452641A5079777926 @default.
• W2979452641 hasAuthorship W2979452641A5085617402 @default.
• W2979452641 hasBestOaLocation W29794526411 @default.
• W2979452641 hasConcept C104317684 @default.
• W2979452641 hasConcept C111425858 @default.
• W2979452641 hasConcept C121608353 @default.
• W2979452641 hasConcept C126322002 @default.
• W2979452641 hasConcept C143998085 @default.
• W2979452641 hasConcept C180754005 @default.
• W2979452641 hasConcept C185592680 @default.
• W2979452641 hasConcept C2776559941 @default.
• W2979452641 hasConcept C2776674815 @default.
• W2979452641 hasConcept C2777701055 @default.
• W2979452641 hasConcept C2778677574 @default.
• W2979452641 hasConcept C2779115348 @default.
• W2979452641 hasConcept C2779767149 @default.
• W2979452641 hasConcept C2780030458 @default.
• W2979452641 hasConcept C526805850 @default.
• W2979452641 hasConcept C55493867 @default.
• W2979452641 hasConcept C60748783 @default.
• W2979452641 hasConcept C61320498 @default.
• W2979452641 hasConcept C71924100 @default.
• W2979452641 hasConceptScore W2979452641C104317684 @default.
• W2979452641 hasConceptScore W2979452641C111425858 @default.
• W2979452641 hasConceptScore W2979452641C121608353 @default.
• W2979452641 hasConceptScore W2979452641C126322002 @default.
• W2979452641 hasConceptScore W2979452641C143998085 @default.
• W2979452641 hasConceptScore W2979452641C180754005 @default.
• W2979452641 hasConceptScore W2979452641C185592680 @default.
• W2979452641 hasConceptScore W2979452641C2776559941 @default.
• W2979452641 hasConceptScore W2979452641C2776674815 @default.
• W2979452641 hasConceptScore W2979452641C2777701055 @default.
• W2979452641 hasConceptScore W2979452641C2778677574 @default.
• W2979452641 hasConceptScore W2979452641C2779115348 @default.
• W2979452641 hasConceptScore W2979452641C2779767149 @default.
• W2979452641 hasConceptScore W2979452641C2780030458 @default.
• W2979452641 hasConceptScore W2979452641C526805850 @default.
• W2979452641 hasConceptScore W2979452641C55493867 @default.
• W2979452641 hasConceptScore W2979452641C60748783 @default.
• W2979452641 hasConceptScore W2979452641C61320498 @default.
• W2979452641 hasConceptScore W2979452641C71924100 @default.
• W2979452641 hasLocation W29794526411 @default.
• W2979452641 hasOpenAccess W2979452641 @default.
• W2979452641 hasPrimaryLocation W29794526411 @default.
• W2979452641 hasRelatedWork W1663153674 @default.
• W2979452641 hasRelatedWork W2132383396 @default.
• W2979452641 hasRelatedWork W2259826353 @default.
• W2979452641 hasRelatedWork W2546257383 @default.
• W2979452641 hasRelatedWork W2567334173 @default.
• W2979452641 hasRelatedWork W2734381437 @default.
• W2979452641 hasRelatedWork W2891826593 @default.
• W2979452641 hasRelatedWork W2897071269 @default.
• W2979452641 hasRelatedWork W2911032670 @default.
• W2979452641 hasRelatedWork W2946552652 @default.
• W2979452641 hasRelatedWork W2966533174 @default.
• W2979452641 hasRelatedWork W2981973548 @default.
• W2979452641 hasRelatedWork W2987320134 @default.
• W2979452641 hasRelatedWork W2999194172 @default.
• W2979452641 hasRelatedWork W3043942060 @default.
• W2979452641 hasRelatedWork W3048746454 @default.
• W2979452641 hasRelatedWork W3118463416 @default.
• W2979452641 hasRelatedWork W3170095987 @default.
• W2979452641 hasRelatedWork W3204499753 @default.
• W2979452641 hasRelatedWork W3206894887 @default.
• W2979452641 hasVolume "30" @default.
• W2979452641 isParatext "false" @default.
• W2979452641 isRetracted "false" @default.

• next