Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979541008> ?p ?o ?g. }
- W2979541008 endingPage "1018" @default.
- W2979541008 startingPage "1009" @default.
- W2979541008 abstract "Summary Background Patients with IBD are at risk of excess corticosteroids. Aims To assess steroid excess in a large IBD cohort and test associations with quality improvement and prescribing. Methods Steroid exposure was recorded for outpatients attending 19 centres and associated factors analysed. Measures taken to avoid excess were assessed. Results Of 2385 patients, 28% received steroids in the preceding 12 months. 14.8% had steroid excess or dependency. Steroid use was significantly lower at ‘intervention centres’ which participated in a quality improvement programme (exposure: 23.8% vs 31.0%, P < .001; excess 11.5% vs 17.1%, P < .001). At intervention centres, steroid use fell from 2015 to 2017 (steroid exposure 30.0%‐23.8%, P = .003; steroid excess 13.8%‐11.5%, P = .17). Steroid excess was judged avoidable in 50.7%. Factors independently associated with reduced steroid excess in Crohn's disease included maintenance with anti‐TNF agents (OR 0.61 [95% CI 0.24‐0.95]), treatment in a centre with a multi‐disciplinary team (OR 0.54 [95% CI 0.20‐0.86]) and treatment at an intervention centre (OR 0.72 [95% CI 0.46‐0.97]). Treatment with 5‐ASA in CD was associated with higher rates of steroid excess (OR 1.72 [95% CI 1.24‐2.09]). In ulcerative colitis (UC), thiopurine monotherapy was associated with steroid excess (OR 1.97 [95% CI 1.19‐3.01]) and treatment at an intervention centre with less steroid excess (OR 0.72 [95% CI 0.45‐0.95]). Conclusions This study validates steroid assessment as a meaningful quality measure and provides a benchmark for this performance indicator in a large cohort. A programme of quality improvement was associated with lower steroid use." @default.
- W2979541008 created "2019-10-18" @default.
- W2979541008 creator A5003997963 @default.
- W2979541008 creator A5005125830 @default.
- W2979541008 creator A5013863005 @default.
- W2979541008 creator A5023947215 @default.
- W2979541008 creator A5027011365 @default.
- W2979541008 creator A5033826764 @default.
- W2979541008 creator A5034081304 @default.
- W2979541008 creator A5042181920 @default.
- W2979541008 creator A5044229367 @default.
- W2979541008 creator A5049943066 @default.
- W2979541008 creator A5051452881 @default.
- W2979541008 creator A5053410116 @default.
- W2979541008 creator A5057064465 @default.
- W2979541008 creator A5059507349 @default.
- W2979541008 creator A5060476085 @default.
- W2979541008 creator A5061023789 @default.
- W2979541008 creator A5065042328 @default.
- W2979541008 creator A5076631930 @default.
- W2979541008 creator A5083860424 @default.
- W2979541008 creator A5089502195 @default.
- W2979541008 creator A5090854255 @default.
- W2979541008 date "2019-10-08" @default.
- W2979541008 modified "2023-10-02" @default.
- W2979541008 title "Assessment of steroid use as a key performance indicator in inflammatory bowel disease—analysis of data from 2385 UK patients" @default.
- W2979541008 cites W1603937579 @default.
- W2979541008 cites W2020033062 @default.
- W2979541008 cites W2064565128 @default.
- W2979541008 cites W2114118261 @default.
- W2979541008 cites W2120522488 @default.
- W2979541008 cites W2156250460 @default.
- W2979541008 cites W2164611094 @default.
- W2979541008 cites W2269809107 @default.
- W2979541008 cites W2468039607 @default.
- W2979541008 cites W2469581016 @default.
- W2979541008 cites W2469587942 @default.
- W2979541008 cites W2523706394 @default.
- W2979541008 cites W2558680180 @default.
- W2979541008 cites W2583633660 @default.
- W2979541008 cites W2601784767 @default.
- W2979541008 cites W2760504294 @default.
- W2979541008 cites W2783948361 @default.
- W2979541008 cites W2910430279 @default.
- W2979541008 cites W4255533032 @default.
- W2979541008 doi "https://doi.org/10.1111/apt.15497" @default.
- W2979541008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31595533" @default.
- W2979541008 hasPublicationYear "2019" @default.
- W2979541008 type Work @default.
- W2979541008 sameAs 2979541008 @default.
- W2979541008 citedByCount "30" @default.
- W2979541008 countsByYear W29795410082020 @default.
- W2979541008 countsByYear W29795410082021 @default.
- W2979541008 countsByYear W29795410082022 @default.
- W2979541008 countsByYear W29795410082023 @default.
- W2979541008 crossrefType "journal-article" @default.
- W2979541008 hasAuthorship W2979541008A5003997963 @default.
- W2979541008 hasAuthorship W2979541008A5005125830 @default.
- W2979541008 hasAuthorship W2979541008A5013863005 @default.
- W2979541008 hasAuthorship W2979541008A5023947215 @default.
- W2979541008 hasAuthorship W2979541008A5027011365 @default.
- W2979541008 hasAuthorship W2979541008A5033826764 @default.
- W2979541008 hasAuthorship W2979541008A5034081304 @default.
- W2979541008 hasAuthorship W2979541008A5042181920 @default.
- W2979541008 hasAuthorship W2979541008A5044229367 @default.
- W2979541008 hasAuthorship W2979541008A5049943066 @default.
- W2979541008 hasAuthorship W2979541008A5051452881 @default.
- W2979541008 hasAuthorship W2979541008A5053410116 @default.
- W2979541008 hasAuthorship W2979541008A5057064465 @default.
- W2979541008 hasAuthorship W2979541008A5059507349 @default.
- W2979541008 hasAuthorship W2979541008A5060476085 @default.
- W2979541008 hasAuthorship W2979541008A5061023789 @default.
- W2979541008 hasAuthorship W2979541008A5065042328 @default.
- W2979541008 hasAuthorship W2979541008A5076631930 @default.
- W2979541008 hasAuthorship W2979541008A5083860424 @default.
- W2979541008 hasAuthorship W2979541008A5089502195 @default.
- W2979541008 hasAuthorship W2979541008A5090854255 @default.
- W2979541008 hasBestOaLocation W29795410082 @default.
- W2979541008 hasConcept C126322002 @default.
- W2979541008 hasConcept C2778260677 @default.
- W2979541008 hasConcept C2779134260 @default.
- W2979541008 hasConcept C2780479503 @default.
- W2979541008 hasConcept C2780902042 @default.
- W2979541008 hasConcept C2909375446 @default.
- W2979541008 hasConcept C70917649 @default.
- W2979541008 hasConcept C71315377 @default.
- W2979541008 hasConcept C71924100 @default.
- W2979541008 hasConcept C72563966 @default.
- W2979541008 hasConcept C90924648 @default.
- W2979541008 hasConceptScore W2979541008C126322002 @default.
- W2979541008 hasConceptScore W2979541008C2778260677 @default.
- W2979541008 hasConceptScore W2979541008C2779134260 @default.
- W2979541008 hasConceptScore W2979541008C2780479503 @default.
- W2979541008 hasConceptScore W2979541008C2780902042 @default.
- W2979541008 hasConceptScore W2979541008C2909375446 @default.
- W2979541008 hasConceptScore W2979541008C70917649 @default.
- W2979541008 hasConceptScore W2979541008C71315377 @default.
- W2979541008 hasConceptScore W2979541008C71924100 @default.