FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979810753> ?p ?o ?g. }

• W2979810753 endingPage "25" @default.
• W2979810753 startingPage "25" @default.
• W2979810753 abstract "Importance Randomized clinical trials have shown the efficacy of thrombectomy of large intracranial vessel occlusions in adults; however, any association of therapy with clinical outcomes in children is unknown. Objective To evaluate the use of endovascular recanalization in pediatric patients with arterial ischemic stroke. Design, Setting, and Participants This retrospective, multicenter cohort study, conducted from January 1, 2000, to December 31, 2018, analyzed the databases from 27 stroke centers in Europe and the United States. Included were all pediatric patients ( Exposures Endovascular recanalization. Main Outcomes and Measures The decrease of the Pediatric National Institutes of Health Stroke Scale (PedNIHSS) score from admission to day 7 was the primary outcome (score range: 0 [no deficit] to 34 [maximum deficit]). Secondary clinical outcomes included the modified Rankin scale (mRS) (score range: 0 [no deficit] to 6 [death]) at 6 and 24 months and rate of complications. Results Seventy-three children from 27 participating stroke centers were included. Median age was 11.3 years (interquartile range [IQR], 7.0-15.0); 37 patients (51%) were boys, and 36 patients (49%) were girls. Sixty-three children (86%) received treatment for anterior circulation occlusion and 10 patients (14%) received treatment for posterior circulation occlusion; 16 patients (22%) received concomitant intravenous thrombolysis. Neurologic outcome improved from a median PedNIHSS score of 14.0 (IQR, 9.2-20.0) at admission to 4.0 (IQR, 2.0-7.3) at day 7. Median mRS score was 1.0 (IQR, 0-1.6) at 6 months and 1.0 (IQR, 0-1.0) at 24 months. One patient (1%) developed a postinterventional bleeding complication and 4 patients (5%) developed transient peri-interventional vasospasm. The proportion of symptomatic intracerebral hemorrhage events in the HERMES meta-analysis of trials with adults was 2.79 (95% CI, 0.42-6.66) and in Save ChildS was 1.37 (95% CI, 0.03-7.40). Conclusions and Relevance The results of this study suggest that the safety profile of thrombectomy in childhood stroke does not differ from the safety profile in randomized clinical trials for adults; most of the treated children had favorable neurologic outcomes. This study may support clinicians’ practice of off-label thrombectomy in childhood stroke in the absence of high-level evidence." @default.
• W2979810753 created "2019-10-18" @default.
• W2979810753 creator A5000216110 @default.
• W2979810753 creator A5000710078 @default.
• W2979810753 creator A5004553220 @default.
• W2979810753 creator A5006544972 @default.
• W2979810753 creator A5006550776 @default.
• W2979810753 creator A5007568960 @default.
• W2979810753 creator A5009403087 @default.
• W2979810753 creator A5009831302 @default.
• W2979810753 creator A5014165648 @default.
• W2979810753 creator A5020509478 @default.
• W2979810753 creator A5020637616 @default.
• W2979810753 creator A5022489433 @default.
• W2979810753 creator A5022948027 @default.
• W2979810753 creator A5023138468 @default.
• W2979810753 creator A5027833721 @default.
• W2979810753 creator A5029064436 @default.
• W2979810753 creator A5030293383 @default.
• W2979810753 creator A5031560071 @default.
• W2979810753 creator A5033205457 @default.
• W2979810753 creator A5033628487 @default.
• W2979810753 creator A5034035251 @default.
• W2979810753 creator A5036245579 @default.
• W2979810753 creator A5037841799 @default.
• W2979810753 creator A5040103619 @default.
• W2979810753 creator A5046375704 @default.
• W2979810753 creator A5049618180 @default.
• W2979810753 creator A5050486324 @default.
• W2979810753 creator A5058748052 @default.
• W2979810753 creator A5058868323 @default.
• W2979810753 creator A5061175108 @default.
• W2979810753 creator A5066204099 @default.
• W2979810753 creator A5066627009 @default.
• W2979810753 creator A5069196425 @default.
• W2979810753 creator A5069273025 @default.
• W2979810753 creator A5071144602 @default.
• W2979810753 creator A5075872750 @default.
• W2979810753 creator A5079484578 @default.
• W2979810753 creator A5083741311 @default.
• W2979810753 creator A5083896047 @default.
• W2979810753 creator A5084206650 @default.
• W2979810753 creator A5084473005 @default.
• W2979810753 creator A5088959058 @default.
• W2979810753 date "2020-01-01" @default.
• W2979810753 modified "2023-10-18" @default.
• W2979810753 title "Feasibility, Safety, and Outcome of Endovascular Recanalization in Childhood Stroke" @default.
• W2979810753 cites W1990405213 @default.
• W2979810753 cites W1996290607 @default.
• W2979810753 cites W1999482579 @default.
• W2979810753 cites W2030349406 @default.
• W2979810753 cites W2037399775 @default.
• W2979810753 cites W2046198140 @default.
• W2979810753 cites W2061854453 @default.
• W2979810753 cites W2073078878 @default.
• W2979810753 cites W2119542322 @default.
• W2979810753 cites W2129854180 @default.
• W2979810753 cites W2139621750 @default.
• W2979810753 cites W2141116224 @default.
• W2979810753 cites W2143237216 @default.
• W2979810753 cites W2171058244 @default.
• W2979810753 cites W2277258071 @default.
• W2979810753 cites W2487774742 @default.
• W2979810753 cites W2511388967 @default.
• W2979810753 cites W2535348557 @default.
• W2979810753 cites W2581487214 @default.
• W2979810753 cites W2617364419 @default.
• W2979810753 cites W2621392879 @default.
• W2979810753 cites W2767776410 @default.
• W2979810753 cites W2780845477 @default.
• W2979810753 cites W2916358774 @default.
• W2979810753 cites W4247071975 @default.
• W2979810753 cites W4247109460 @default.
• W2979810753 cites W4255683973 @default.
• W2979810753 cites W4292528167 @default.
• W2979810753 doi "https://doi.org/10.1001/jamaneurol.2019.3403" @default.
• W2979810753 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6802048" @default.
• W2979810753 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31609380" @default.
• W2979810753 hasPublicationYear "2020" @default.
• W2979810753 type Work @default.
• W2979810753 sameAs 2979810753 @default.
• W2979810753 citedByCount "100" @default.
• W2979810753 countsByYear W29798107532020 @default.
• W2979810753 countsByYear W29798107532021 @default.
• W2979810753 countsByYear W29798107532022 @default.
• W2979810753 countsByYear W29798107532023 @default.
• W2979810753 crossrefType "journal-article" @default.
• W2979810753 hasAuthorship W2979810753A5000216110 @default.
• W2979810753 hasAuthorship W2979810753A5000710078 @default.
• W2979810753 hasAuthorship W2979810753A5004553220 @default.
• W2979810753 hasAuthorship W2979810753A5006544972 @default.
• W2979810753 hasAuthorship W2979810753A5006550776 @default.
• W2979810753 hasAuthorship W2979810753A5007568960 @default.
• W2979810753 hasAuthorship W2979810753A5009403087 @default.
• W2979810753 hasAuthorship W2979810753A5009831302 @default.
• W2979810753 hasAuthorship W2979810753A5014165648 @default.
• W2979810753 hasAuthorship W2979810753A5020509478 @default.
• W2979810753 hasAuthorship W2979810753A5020637616 @default.

• next