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- W2979837306 abstract "INTRODUCTION: The incidence of colorectal cancer has been on the rise in young and middle aged adults in the United States. While adenocarcinoma remains the most common type of colorectal cancer, lymphoma, particularly mantle cell lymphoma (MCL) is a rare type of lymphoma that can occur in those between the ages of 35-85. We present a case of MCL seen during routine colonoscopy. CASE DESCRIPTION/METHODS: A 51 year old male with recent diagnosis of MCL by oncology was referred to gastroenterology for a screening colonoscopy. During the procedure innumerable large polypoid lesions were visualized in the cecum and ascending colon with similar findings scattered throughout the colon. Biopsies taken from the ascending colon revealed dense atypical lymphoid proliferation with immunohistochemistry confirming MCL. DISCUSSION: MCL comprises about 7% of non-Hodgkin lymphomas. Extranodal manifestations of MCL occurs in 25% of those that are newly diagnosed, with GI involvement estimated to be 15-60%. At the time of diagnosis, most patients present in the advanced stages of MCL. It is associated with poor long term survival and high relapse rates. However, recent advances in potential new therapies for MCL have shown promise. Our case is unusual in that the typical signs of intestinal malaise (abdominal pain, diarrhea, anorexia, and hematochezia) and/or systemic B symptoms were not present. With remission rates being dismal, and treatment strategies based on patient fitness and symptoms, early detection is imperative. It is important to be cognizant to the complaints patients have as it may warrant earlier colonoscopy and therefore diagnosis of colorectal cancer." @default.
- W2979837306 created "2019-10-18" @default.
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- W2979837306 date "2019-10-01" @default.
- W2979837306 modified "2023-09-23" @default.
- W2979837306 title "3049 Mantle Cell Lymphoma in Routine Screening Colonoscopy" @default.
- W2979837306 doi "https://doi.org/10.14309/01.ajg.0000601728.88501.bd" @default.
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