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- W2979861306 abstract "The evidence for the involvement of natural killer (NK) cells in host resistance against tumor growth in vivo is primarily based on the correlation between the levels of NK cell-mediated cytotoxicity (CMC) in vitro and the inhibition of the growth of small inocula of NK-sensitive tumor cells. To assess the possible role of NK cells in host defenses against tumor growth and metastasis, investigators have studied the in vivo growth characteristics of NK-sensitive or NK-resistant tumor cells in hosts that exhibit low or high levels of NK CMC. Thus, in mice of various genotypes, ages, and F1 hybrid combinations, the resistance against the growth of YAC and other lymphoma cells correlated with the levels of NK cell activity of the host. The multiplicity of host effector mechanisms involved in resistance against tumor growth and metastasis already suggests that no single mechanism could be identified as being solely responsible for the antimetastatic activity in vivo." @default.
- W2979861306 created "2019-10-18" @default.
- W2979861306 creator A5074473587 @default.
- W2979861306 date "2019-07-23" @default.
- W2979861306 modified "2023-09-24" @default.
- W2979861306 title "In Vivo Activities of NK Cells Against Primary and Metastatic Tumors in Experimental Animals" @default.
- W2979861306 doi "https://doi.org/10.1201/9780429288364-1" @default.
- W2979861306 hasPublicationYear "2019" @default.
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