FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979865764> ?p ?o ?g. }

• W2979865764 endingPage "584" @default.
• W2979865764 startingPage "576" @default.
• W2979865764 abstract "Because of the risk of bacterial biofilm infections, prophylactic use of antibiotics in orthopaedic procedures involving the implantation of large prosthesis systems is considered mandatory. A strategy based on the rationale that local antibiotics released from bone cement or other carriers establish a second antibacterial frontline in and around the prosthesis is considered complementary to the administration of systemic antibiotics. Although less common as a consequence of the initially very high drug concentrations of local antibiotics in the tissues, a selection process of previous high resistance bacteria may occur, leading to antibiotic resistance. The use of antibiotic combinations in bone cement is generally accepted to improve antibiotic efficacy and minimizes the treatment failure risk due to antibiotic resistance. This is important in septic revisions and/or in patients at particularly high risk of infection. On an individual basis, the benefit of a lower infection probability with combined systemic and local antibiotic application should outweigh the risk of the selection of more resistant bacteria. Each prevented infection means that a complex and extended antibiotic therapy with risk of resistance development over time has been avoided. On an epidemiological level there is no clinical evidence that the routine use of bone cement impregnated with appropriate bactericidal antibiotics promotes the widespread development of antibiotic resistance and thereby puts the successful treatment of a prosthetic joint infection at higher risk. Cite this article: EFORT Open Rev 2019;4:576-584. DOI: 10.1302/2058-5241.4.180104" @default.
• W2979865764 created "2019-10-18" @default.
• W2979865764 creator A5007561948 @default.
• W2979865764 creator A5011829991 @default.
• W2979865764 date "2019-10-01" @default.
• W2979865764 modified "2023-10-17" @default.
• W2979865764 title "Risk assessment of antibiotic resistance development by antibiotic-loaded bone cements: is it a clinical concern?" @default.
• W2979865764 cites W1555735784 @default.
• W2979865764 cites W1775842101 @default.
• W2979865764 cites W1787488026 @default.
• W2979865764 cites W1804570358 @default.
• W2979865764 cites W1854330039 @default.
• W2979865764 cites W1930890996 @default.
• W2979865764 cites W1977912753 @default.
• W2979865764 cites W1987599774 @default.
• W2979865764 cites W1994288441 @default.
• W2979865764 cites W1997998296 @default.
• W2979865764 cites W2001144005 @default.
• W2979865764 cites W2005374587 @default.
• W2979865764 cites W2015774835 @default.
• W2979865764 cites W2038186111 @default.
• W2979865764 cites W2044183854 @default.
• W2979865764 cites W2075182144 @default.
• W2979865764 cites W2086704116 @default.
• W2979865764 cites W2102823237 @default.
• W2979865764 cites W2103823187 @default.
• W2979865764 cites W2104248768 @default.
• W2979865764 cites W2126949149 @default.
• W2979865764 cites W2132505663 @default.
• W2979865764 cites W2141017707 @default.
• W2979865764 cites W2156772861 @default.
• W2979865764 cites W2159254568 @default.
• W2979865764 cites W2187199690 @default.
• W2979865764 cites W2212259890 @default.
• W2979865764 cites W2326845225 @default.
• W2979865764 cites W2413451270 @default.
• W2979865764 cites W2550348418 @default.
• W2979865764 cites W2560610835 @default.
• W2979865764 cites W2618749092 @default.
• W2979865764 cites W2757444754 @default.
• W2979865764 cites W2808022087 @default.
• W2979865764 cites W2894812081 @default.
• W2979865764 cites W2942654206 @default.
• W2979865764 cites W2975446383 @default.
• W2979865764 cites W4254830184 @default.
• W2979865764 doi "https://doi.org/10.1302/2058-5241.4.180104" @default.
• W2979865764 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6836079" @default.
• W2979865764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31754463" @default.
• W2979865764 hasPublicationYear "2019" @default.
• W2979865764 type Work @default.
• W2979865764 sameAs 2979865764 @default.
• W2979865764 citedByCount "23" @default.
• W2979865764 countsByYear W29798657642020 @default.
• W2979865764 countsByYear W29798657642021 @default.
• W2979865764 countsByYear W29798657642022 @default.
• W2979865764 countsByYear W29798657642023 @default.
• W2979865764 crossrefType "journal-article" @default.
• W2979865764 hasAuthorship W2979865764A5007561948 @default.
• W2979865764 hasAuthorship W2979865764A5011829991 @default.
• W2979865764 hasBestOaLocation W29798657641 @default.
• W2979865764 hasConcept C177713679 @default.
• W2979865764 hasConcept C191897082 @default.
• W2979865764 hasConcept C192562407 @default.
• W2979865764 hasConcept C2778891590 @default.
• W2979865764 hasConcept C501593827 @default.
• W2979865764 hasConcept C523993062 @default.
• W2979865764 hasConcept C71924100 @default.
• W2979865764 hasConcept C86803240 @default.
• W2979865764 hasConcept C89423630 @default.
• W2979865764 hasConcept C94665300 @default.
• W2979865764 hasConceptScore W2979865764C177713679 @default.
• W2979865764 hasConceptScore W2979865764C191897082 @default.
• W2979865764 hasConceptScore W2979865764C192562407 @default.
• W2979865764 hasConceptScore W2979865764C2778891590 @default.
• W2979865764 hasConceptScore W2979865764C501593827 @default.
• W2979865764 hasConceptScore W2979865764C523993062 @default.
• W2979865764 hasConceptScore W2979865764C71924100 @default.
• W2979865764 hasConceptScore W2979865764C86803240 @default.
• W2979865764 hasConceptScore W2979865764C89423630 @default.
• W2979865764 hasConceptScore W2979865764C94665300 @default.
• W2979865764 hasIssue "10" @default.
• W2979865764 hasLocation W29798657641 @default.
• W2979865764 hasLocation W29798657642 @default.
• W2979865764 hasLocation W29798657643 @default.
• W2979865764 hasLocation W29798657644 @default.
• W2979865764 hasOpenAccess W2979865764 @default.
• W2979865764 hasPrimaryLocation W29798657641 @default.
• W2979865764 hasRelatedWork W2067089984 @default.
• W2979865764 hasRelatedWork W2149075985 @default.
• W2979865764 hasRelatedWork W2415330112 @default.
• W2979865764 hasRelatedWork W2853025534 @default.
• W2979865764 hasRelatedWork W2943133603 @default.
• W2979865764 hasRelatedWork W3083932983 @default.
• W2979865764 hasRelatedWork W3120685386 @default.
• W2979865764 hasRelatedWork W3166274739 @default.
• W2979865764 hasRelatedWork W3213927646 @default.
• W2979865764 hasRelatedWork W4280637011 @default.
• W2979865764 hasVolume "4" @default.

• next