Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979882008> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2979882008 endingPage "17" @default.
- W2979882008 startingPage "13" @default.
- W2979882008 abstract "Polymorphism of dinucleotide microsatellite in the aldose reductase (AR2) gene and two polymorphic microsatellite markers (DI 1S907 and DI IS2008) near catalase (CAT) gene were studied in insulin-dependent diabetics with and without diabetic nephropathy (DN). We formed the groups of patients to compare using the extremephenotypeapproach. Twenty-seven proteinuric patients with relatively short diabetes duration (<15 years) and 41 patients with a longer diabetes duration (>20years) without signs of DNserved as the case(DN+) and control(DN-) groups, respectively. Seven alleles of the AR2 gene ranging from 132 to 144 base pairs (bp) long were detected. For DI 1S907 and DI 1S2008, seven and eight alleles from 161 to 173 and from 120 to 148 bp long were found, respectively. No significant differences in the distribution of alleles and genotypes of AR2 and DI IS2008 loci in the DN+ and DN— groups were detected by Fisher's test. For D11S907, a significant increase in the frequency of both 15 (16.7% vs. 6.1%), p<0.05) and 18 (29.6%) vs. 15.9%, p<0.05) alleles was revealed in DNpatients in comparison with the controls, while the 17 allele of D11S907 was significantly rarer (9.3% vs. 30.5%, p<0.005) in the nephropaths than in diabetics without DN. Hence, the polymorphism of the AR2 gene is not associated with DN in IDDM, while a chromosome region near the CA T gene is likely to be linked with the disorder." @default.
- W2979882008 created "2019-10-18" @default.
- W2979882008 creator A5006132528 @default.
- W2979882008 creator A5006198250 @default.
- W2979882008 creator A5030271532 @default.
- W2979882008 creator A5038977238 @default.
- W2979882008 creator A5046498814 @default.
- W2979882008 creator A5063507725 @default.
- W2979882008 creator A5076228526 @default.
- W2979882008 creator A5087161156 @default.
- W2979882008 date "1999-10-15" @default.
- W2979882008 modified "2023-09-25" @default.
- W2979882008 title "Polymorphism of microsatellite markers of aldose reductase and catalase genes and a genetic predisposition to nephropathy in insulin-dependent diabetes mellitus" @default.
- W2979882008 doi "https://doi.org/10.14341/probl11797" @default.
- W2979882008 hasPublicationYear "1999" @default.
- W2979882008 type Work @default.
- W2979882008 sameAs 2979882008 @default.
- W2979882008 citedByCount "1" @default.
- W2979882008 crossrefType "journal-article" @default.
- W2979882008 hasAuthorship W2979882008A5006132528 @default.
- W2979882008 hasAuthorship W2979882008A5006198250 @default.
- W2979882008 hasAuthorship W2979882008A5030271532 @default.
- W2979882008 hasAuthorship W2979882008A5038977238 @default.
- W2979882008 hasAuthorship W2979882008A5046498814 @default.
- W2979882008 hasAuthorship W2979882008A5063507725 @default.
- W2979882008 hasAuthorship W2979882008A5076228526 @default.
- W2979882008 hasAuthorship W2979882008A5087161156 @default.
- W2979882008 hasBestOaLocation W29798820081 @default.
- W2979882008 hasConcept C104317684 @default.
- W2979882008 hasConcept C126322002 @default.
- W2979882008 hasConcept C134018914 @default.
- W2979882008 hasConcept C135763542 @default.
- W2979882008 hasConcept C180754005 @default.
- W2979882008 hasConcept C2776439734 @default.
- W2979882008 hasConcept C2779922275 @default.
- W2979882008 hasConcept C2781184683 @default.
- W2979882008 hasConcept C54355233 @default.
- W2979882008 hasConcept C555293320 @default.
- W2979882008 hasConcept C61320498 @default.
- W2979882008 hasConcept C71924100 @default.
- W2979882008 hasConcept C86803240 @default.
- W2979882008 hasConceptScore W2979882008C104317684 @default.
- W2979882008 hasConceptScore W2979882008C126322002 @default.
- W2979882008 hasConceptScore W2979882008C134018914 @default.
- W2979882008 hasConceptScore W2979882008C135763542 @default.
- W2979882008 hasConceptScore W2979882008C180754005 @default.
- W2979882008 hasConceptScore W2979882008C2776439734 @default.
- W2979882008 hasConceptScore W2979882008C2779922275 @default.
- W2979882008 hasConceptScore W2979882008C2781184683 @default.
- W2979882008 hasConceptScore W2979882008C54355233 @default.
- W2979882008 hasConceptScore W2979882008C555293320 @default.
- W2979882008 hasConceptScore W2979882008C61320498 @default.
- W2979882008 hasConceptScore W2979882008C71924100 @default.
- W2979882008 hasConceptScore W2979882008C86803240 @default.
- W2979882008 hasIssue "5" @default.
- W2979882008 hasLocation W29798820081 @default.
- W2979882008 hasOpenAccess W2979882008 @default.
- W2979882008 hasPrimaryLocation W29798820081 @default.
- W2979882008 hasRelatedWork W1978293874 @default.
- W2979882008 hasRelatedWork W2032111989 @default.
- W2979882008 hasRelatedWork W2038657938 @default.
- W2979882008 hasRelatedWork W2047956456 @default.
- W2979882008 hasRelatedWork W2057739827 @default.
- W2979882008 hasRelatedWork W2075016875 @default.
- W2979882008 hasRelatedWork W2104195310 @default.
- W2979882008 hasRelatedWork W2131426370 @default.
- W2979882008 hasRelatedWork W2132042562 @default.
- W2979882008 hasRelatedWork W2406277046 @default.
- W2979882008 hasVolume "45" @default.
- W2979882008 isParatext "false" @default.
- W2979882008 isRetracted "false" @default.
- W2979882008 magId "2979882008" @default.
- W2979882008 workType "article" @default.