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• W2979897448 abstract "This systematic review summarizes the data on the prevalence, risk factors, complications, and management of atrial fibrillation (AF) in sub-Saharan Africa (SSA). Bibliographic databases were searched from inception to 31 May 2019, to identify all published studies providing data on AF in populations living in SSA. A total of 72 studies were included. The community-based prevalence of AF was 4.3% and 0.7% in individuals aged ≥40 years and aged ≥70 years, respectively. The prevalence of AF ranged between 6.7% and 34.8% in patients with ischemic stroke, between 9.5% and 46.8% in those with rheumatic heart disease (RHD), between 5% and 31.5% in patients with dilated cardiomyopathy. The main risk factors for AF were hypertension, affecting at least one-third of patients with AF, and valvular heart disease (12.3%-44.4%) and cardiomyopathy (~20%). Complications of AF included heart failure in about two thirds and stroke in 10% to 15% of cases. The use of anticoagulation for stroke prevention was suboptimal. Rate control was the most frequent therapeutic strategy, used in approximately 65% to 95% of AF patients, with approximately 80% of them achieving rate control. The management of AF was associated with exorbitant cost. In conclusion, AF seems to have a higher prevalence in the general population than previously thought and is mostly associated with hypertension, cardiomyopathy, and RHD in SSA. It is associated with a high incidence of heart failure and stroke. The management of AF is suboptimal in SSA, especially with a low uptake of oral anticoagulation." @default.
• W2979897448 created "2019-10-18" @default.
• W2979897448 creator A5070940808 @default.
• W2979897448 creator A5071035873 @default.
• W2979897448 date "2019-11-10" @default.
• W2979897448 modified "2023-10-17" @default.
• W2979897448 title "A review of the epidemiology of atrial fibrillation in sub‐Saharan Africa" @default.
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• W2979897448 doi "https://doi.org/10.1111/jce.14222" @default.
• W2979897448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31596016" @default.
• W2979897448 hasPublicationYear "2019" @default.
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