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• W2980196058 abstract "Hepatitis E virus (HEV) is a significant health problem with approximately 20 million individuals infected annually. HEV infection has been associated with a wide spectrum of extrahepatic manifestations, including neurological, hematological and renal disorders. Guillain-Barré syndrome and neuralgic amyotrophy are the most frequent neurological manifestations. In addition, HEV infection has been observed with other neurological diseases, such as encephalitis, myelitis and Bell’s palsy. Hematologic manifestations include anemia due to glucose-6-phospate dehydrogonase deficiency, autoimmune hemolytic anemia and severe thrombocytopenia. Membranoproliferative glomerulonephritis and relapse IgA nephropathy with or without coexisting cryoglobulinemia appear to be the most common renal injuries related with HEV infection. Also, HEV infection has been associated with acute pancreatitis and other immune-mediated manifestations, such as arthritis and myocarditis. However, the pathophysiologic mechanisms of HEV-related extrahepatic manifestations are still largely unclear. Keywords: Hepatitis E; Kidney; Neurologic manifestations; Hematologic diseases" @default.
• W2980196058 created "2019-10-18" @default.
• W2980196058 creator A5017642140 @default.
• W2980196058 creator A5046570350 @default.
• W2980196058 creator A5075366945 @default.
• W2980196058 date "2020-01-01" @default.
• W2980196058 modified "2023-10-01" @default.
• W2980196058 title "Extrahepatic manifestations of hepatitis E virus: An overview" @default.
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• W2980196058 doi "https://doi.org/10.3350/cmh.2019.0082" @default.
• W2980196058 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6940480" @default.
• W2980196058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31601068" @default.
• W2980196058 hasPublicationYear "2020" @default.
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