FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980198451> ?p ?o ?g. }

• W2980198451 endingPage "590" @default.
• W2980198451 startingPage "586" @default.
• W2980198451 abstract "Context: Multiple sclerosis (MS) is an autoimmune and chronic inflammatory disease of CNS. The α-L-guluronic acid (G2013) as novel NSAID with immunomodulatory effects has shown its positive effects in various investigations.Objective: Present research aimed to study the potency of G2013 on gene expression of TLR2, TLR4, MyD88, TNF-α and CD52 in PBMCs of MS patients under in vitro conditions. Materials and methods: 24 blood samples from MS patients and healthy controls were considered for RT-PCR and flow cytometry techniques under two different doses of G2013.Results: Our research indicated that this drug could significantly decrease the gene expression of TLR2, TLR4 and TNF-α compared to untreated group. Conclusion: Data demonstrated that the guluronic acid is able to modify the expression levels of TLR2, TLR4 and TNF-α genes to less than the pathogenic boarder line level, which it might be recommended for reducing the pathological process in multiple sclerosis." @default.
• W2980198451 created "2019-10-18" @default.
• W2980198451 creator A5002216132 @default.
• W2980198451 creator A5003094675 @default.
• W2980198451 creator A5009544793 @default.
• W2980198451 creator A5038491338 @default.
• W2980198451 creator A5050902289 @default.
• W2980198451 creator A5051164690 @default.
• W2980198451 creator A5052050053 @default.
• W2980198451 creator A5055690628 @default.
• W2980198451 creator A5088178285 @default.
• W2980198451 date "2019-10-08" @default.
• W2980198451 modified "2023-09-24" @default.
• W2980198451 title "Effects of guluronic acid (G2013) on gene expression of TLR2, TLR4, MyD88, TNF-α and CD52 in multiple sclerosis under in vitro conditions" @default.
• W2980198451 cites W1856003942 @default.
• W2980198451 cites W1928494949 @default.
• W2980198451 cites W1964107900 @default.
• W2980198451 cites W1977233832 @default.
• W2980198451 cites W2010156984 @default.
• W2980198451 cites W2019522924 @default.
• W2980198451 cites W2021724645 @default.
• W2980198451 cites W2063696028 @default.
• W2980198451 cites W2080709645 @default.
• W2980198451 cites W2085412596 @default.
• W2980198451 cites W2086610416 @default.
• W2980198451 cites W2105491136 @default.
• W2980198451 cites W2130542798 @default.
• W2980198451 cites W2144679012 @default.
• W2980198451 cites W2165451230 @default.
• W2980198451 cites W2312313151 @default.
• W2980198451 cites W2397144303 @default.
• W2980198451 cites W2413269917 @default.
• W2980198451 cites W2482063514 @default.
• W2980198451 cites W2489130503 @default.
• W2980198451 cites W2562989430 @default.
• W2980198451 cites W2584701803 @default.
• W2980198451 cites W2603656304 @default.
• W2980198451 cites W2618958403 @default.
• W2980198451 cites W2732823864 @default.
• W2980198451 cites W2743141330 @default.
• W2980198451 cites W2781735706 @default.
• W2980198451 cites W2781855419 @default.
• W2980198451 cites W2789137799 @default.
• W2980198451 cites W2807888515 @default.
• W2980198451 cites W2822203343 @default.
• W2980198451 cites W2872631810 @default.
• W2980198451 cites W2883141677 @default.
• W2980198451 cites W2884610214 @default.
• W2980198451 cites W4322703314 @default.
• W2980198451 cites W775956452 @default.
• W2980198451 doi "https://doi.org/10.1080/08923973.2019.1672179" @default.
• W2980198451 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31594427" @default.
• W2980198451 hasPublicationYear "2019" @default.
• W2980198451 type Work @default.
• W2980198451 sameAs 2980198451 @default.
• W2980198451 citedByCount "4" @default.
• W2980198451 countsByYear W29801984512021 @default.
• W2980198451 countsByYear W29801984512023 @default.
• W2980198451 crossrefType "journal-article" @default.
• W2980198451 hasAuthorship W2980198451A5002216132 @default.
• W2980198451 hasAuthorship W2980198451A5003094675 @default.
• W2980198451 hasAuthorship W2980198451A5009544793 @default.
• W2980198451 hasAuthorship W2980198451A5038491338 @default.
• W2980198451 hasAuthorship W2980198451A5050902289 @default.
• W2980198451 hasAuthorship W2980198451A5051164690 @default.
• W2980198451 hasAuthorship W2980198451A5052050053 @default.
• W2980198451 hasAuthorship W2980198451A5055690628 @default.
• W2980198451 hasAuthorship W2980198451A5088178285 @default.
• W2980198451 hasConcept C137061746 @default.
• W2980198451 hasConcept C151730666 @default.
• W2980198451 hasConcept C159654299 @default.
• W2980198451 hasConcept C17991360 @default.
• W2980198451 hasConcept C202751555 @default.
• W2980198451 hasConcept C203014093 @default.
• W2980198451 hasConcept C2776070231 @default.
• W2980198451 hasConcept C2776914184 @default.
• W2980198451 hasConcept C2778384904 @default.
• W2980198451 hasConcept C2779015954 @default.
• W2980198451 hasConcept C2779343474 @default.
• W2980198451 hasConcept C2780640218 @default.
• W2980198451 hasConcept C2781236682 @default.
• W2980198451 hasConcept C553184892 @default.
• W2980198451 hasConcept C55493867 @default.
• W2980198451 hasConcept C71924100 @default.
• W2980198451 hasConcept C86803240 @default.
• W2980198451 hasConcept C98274493 @default.
• W2980198451 hasConceptScore W2980198451C137061746 @default.
• W2980198451 hasConceptScore W2980198451C151730666 @default.
• W2980198451 hasConceptScore W2980198451C159654299 @default.
• W2980198451 hasConceptScore W2980198451C17991360 @default.
• W2980198451 hasConceptScore W2980198451C202751555 @default.
• W2980198451 hasConceptScore W2980198451C203014093 @default.
• W2980198451 hasConceptScore W2980198451C2776070231 @default.
• W2980198451 hasConceptScore W2980198451C2776914184 @default.
• W2980198451 hasConceptScore W2980198451C2778384904 @default.
• W2980198451 hasConceptScore W2980198451C2779015954 @default.
• W2980198451 hasConceptScore W2980198451C2779343474 @default.
• W2980198451 hasConceptScore W2980198451C2780640218 @default.

• next