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- W2980332595 endingPage "Doc03" @default.
- W2980332595 startingPage "Doc03" @default.
- W2980332595 abstract "Surgical treatment of laryngeal cancer has been established for decades. In addition to total laryngectomy, which was first performed in 1873, a large number or organ preservation surgical techniques, like open partial laryngectomy, transoral laser microsurgery, and transoral robotic surgery have been developed. Studies on laryngeal cancer surgery are mainly retrospective case series and cohort studies. The evolution of chemoradiation protocols and their analysis in prospective randomized trials have led to an increasing acceptance of non-surgical treatment procedures. In addition to an improvement of prognosis, in recent years the preservation of function and maintenance of life quality after primary therapy of laryngeal cancer has increasingly become the focus of therapy planning. Significant late toxicity after chemoradiation has been identified as an important issue. This leads to a reassessment of surgical concepts and initiation of studies on laryngeal cancer surgery which was additionally stimulated by the advent of transoral robotic surgery in the US. Improving the evidence base of laryngeal cancer surgery by successful establishment of surgical trials should be the future goal." @default.
- W2980332595 created "2019-10-25" @default.
- W2980332595 creator A5085418389 @default.
- W2980332595 date "2016-01-01" @default.
- W2980332595 modified "2023-09-23" @default.
- W2980332595 title "Evidence and evidence gaps of laryngeal cancer surgery." @default.
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