FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980365079> ?p ?o ?g. }

• W2980365079 endingPage "A788" @default.
• W2980365079 startingPage "A787" @default.
• W2980365079 abstract "SESSION TITLE: Monday Medical Student/Resident Case Report Posters SESSION TYPE: Med Student/Res Case Rep Postr PRESENTED ON: 10/21/2019 02:30 PM - 03:15 PM INTRODUCTION: While non-tuberculous mycobacteria (NTM) can cause a wide spectrum of human disease, their association with pleural effusion is unusual (1). We describe a case of Mycobacterium fortuitum empyema in a patient with rheumatoid lung disease who presented with spontaneous secondary pneumothorax. Incidentally, his pleural fluid also revealed chylomicrons suggesting chylothorax. CASE PRESENTATION: A 52 yo male with history of Rheumatoid Arthritis (RA), IV methamphetamine use, chronic asymptomatic bilateral pulmonary nodules and pleural effusions (presumed rheumatoid lung disease) presented with shortness of breath and cough for 5 days. He was hemodynamically stable except for mild tachycardia. Chest X ray revealed right sided pneumothorax. A 9 Fr anterior chest tube was placed with improvement in pneumothorax. Subsequently, milky fluid started draining from the tube. Fluid analysis showed: pH 7.61, RBC 50,000/cu.mm, WBC 64,000/cu.mm with 94% neutrophils, glucose 5 mg/dl, LDH 4344 u/L, protein 5.0 g/dL, amylase 30 U/L, triglyceride 114 mg/dL, ADA 111.8 U/L, chylomicrons present. CT scan showed pulmonary nodules some of which increased in size and cavitated when compared to old scans. Pleural fluid cultures grew mycobacterium within 48 hours which eventually speciated as M. fortuitum. VATS guided right pleural biopsy was performed and multiple biopsy samples grew M. fortuitum. Of note, the same organism grew in his sputum samples as well. DISCUSSION: Rapidly growing mycobacteria rarely cause pulmonary infection, and when it does occur, it is typically from abscessus (2). Pulmonary infection may occur from M. fortuitum, in a patient with known underlying lung disease or immunosuppression (3). Our patient had known asymptomatic pleural effusion and bilateral pulmonary nodules. He presented with spontaneous pneumothorax associated with increase in size of nodules and cavitation. He was on leflunomide and hydroxychloroquine for RA and has also been getting steroids intermittently for RA flares, last given 2 months prior to presentation. It is possible that underlying lung disease and immunosuppression predisposed him to develop M. fortuitum infection, which in turn lead to cavitation of peripheral nodules and pneumothorax. Incidentally, pleural fluid testing also revealed chylomicrons, confirming component of chylous effusion This case suggests that rheumatoid lung disease, especially in setting of steroid therapy is a risk factor for NTM infection, and development of such infection may be heralded by an acute complication such as pneumothorax. CONCLUSIONS: NTM are rarely associated with pleural disease. They should be considered in the differential when an immunocompromised individual with chronic lung disease presents with acute worsening. We describe a rare association of rheumatoid lung disease with M. fortuitum pulmonary infection which lead to acute presentation with chylopyopneumothorax. Reference #1: Johnson MM, Odell JA. Nontuberculous mycobacterial pulmonary infections. J Thorac Dis. 2014;6(3):210-20. Reference #2: Griffith DE, Girard WM, Wallace RJ Jr. Clinical features of pulmonary disease caused by rapidly growing mycobacteria. An analysis of 154 patients. Am Rev Respir Dis. 1993 May;147(5):1271-8. Reference #3: Park S, Suh GY, Chung MP, Kim H, Kwon OJ, Lee KS, Lee NY, Koh WJ. Clinical significance of Mycobacterium fortuitum isolated from respiratory specimens. Respir Med. 2008 Mar;102(3):437-42. Epub 2007 Nov 9. PubMed PMID: 17997087. DISCLOSURES: No relevant relationships by Spyridon Fortis, source=Web Response No relevant relationships by Vikas Koppurapu, source=Web Response no disclosure on file for Matthew McGee; No relevant relationships by Tayyab Rehman, source=Web Response No relevant relationships by Roger Struble, source=Web Response" @default.
• W2980365079 created "2019-10-25" @default.
• W2980365079 creator A5022589577 @default.
• W2980365079 creator A5037410090 @default.
• W2980365079 creator A5065478724 @default.
• W2980365079 creator A5066463993 @default.
• W2980365079 creator A5068104857 @default.
• W2980365079 date "2019-10-01" @default.
• W2980365079 modified "2023-10-18" @default.
• W2980365079 title "CHYLOPYOPNEUMOTHORAX IN A PATIENT WITH RHEUMATOID LUNG DISEASE" @default.
• W2980365079 doi "https://doi.org/10.1016/j.chest.2019.08.757" @default.
• W2980365079 hasPublicationYear "2019" @default.
• W2980365079 type Work @default.
• W2980365079 sameAs 2980365079 @default.
• W2980365079 citedByCount "1" @default.
• W2980365079 countsByYear W29803650792019 @default.
• W2980365079 crossrefType "journal-article" @default.
• W2980365079 hasAuthorship W2980365079A5022589577 @default.
• W2980365079 hasAuthorship W2980365079A5037410090 @default.
• W2980365079 hasAuthorship W2980365079A5065478724 @default.
• W2980365079 hasAuthorship W2980365079A5066463993 @default.
• W2980365079 hasAuthorship W2980365079A5068104857 @default.
• W2980365079 hasBestOaLocation W29803650791 @default.
• W2980365079 hasConcept C126322002 @default.
• W2980365079 hasConcept C141071460 @default.
• W2980365079 hasConcept C142724271 @default.
• W2980365079 hasConcept C2776301714 @default.
• W2980365079 hasConcept C2777063151 @default.
• W2980365079 hasConcept C2777714996 @default.
• W2980365079 hasConcept C2777799383 @default.
• W2980365079 hasConcept C2778329176 @default.
• W2980365079 hasConcept C2779056968 @default.
• W2980365079 hasConcept C2779634585 @default.
• W2980365079 hasConcept C2781069245 @default.
• W2980365079 hasConcept C71924100 @default.
• W2980365079 hasConcept C90924648 @default.
• W2980365079 hasConceptScore W2980365079C126322002 @default.
• W2980365079 hasConceptScore W2980365079C141071460 @default.
• W2980365079 hasConceptScore W2980365079C142724271 @default.
• W2980365079 hasConceptScore W2980365079C2776301714 @default.
• W2980365079 hasConceptScore W2980365079C2777063151 @default.
• W2980365079 hasConceptScore W2980365079C2777714996 @default.
• W2980365079 hasConceptScore W2980365079C2777799383 @default.
• W2980365079 hasConceptScore W2980365079C2778329176 @default.
• W2980365079 hasConceptScore W2980365079C2779056968 @default.
• W2980365079 hasConceptScore W2980365079C2779634585 @default.
• W2980365079 hasConceptScore W2980365079C2781069245 @default.
• W2980365079 hasConceptScore W2980365079C71924100 @default.
• W2980365079 hasConceptScore W2980365079C90924648 @default.
• W2980365079 hasIssue "4" @default.
• W2980365079 hasLocation W29803650791 @default.
• W2980365079 hasOpenAccess W2980365079 @default.
• W2980365079 hasPrimaryLocation W29803650791 @default.
• W2980365079 hasRelatedWork W1529229148 @default.
• W2980365079 hasRelatedWork W1809460789 @default.
• W2980365079 hasRelatedWork W1999479504 @default.
• W2980365079 hasRelatedWork W2067177009 @default.
• W2980365079 hasRelatedWork W2084911436 @default.
• W2980365079 hasRelatedWork W2171257421 @default.
• W2980365079 hasRelatedWork W2283945086 @default.
• W2980365079 hasRelatedWork W2367568243 @default.
• W2980365079 hasRelatedWork W2419031101 @default.
• W2980365079 hasRelatedWork W4247695980 @default.
• W2980365079 hasVolume "156" @default.
• W2980365079 isParatext "false" @default.
• W2980365079 isRetracted "false" @default.
• W2980365079 magId "2980365079" @default.
• W2980365079 workType "article" @default.