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- W2980372150 abstract "Bortezomib is a proteasome inhibitor commonly used for the treatment of multiple myeloma (MM). Its proven efficacy has resulted in increased survival rates in both the newly diagnosed and relapsed/refractory cohorts. Bortezomib-induced peripheral neuropathy (BIPN) is a disabling and common toxicity associated with this treatment, typically requiring dose reduction, delay or cessation of treatment protocol. It typically presents as numbness, tingling and paraesthesia manifesting in the peripheral domain in a glove and stocking distribution. Aims: This review aimed to investigate the incidence, risk factors, trends and variability associated with the development of BIPN." @default.
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- W2980372150 date "2019-10-01" @default.
- W2980372150 modified "2023-09-27" @default.
- W2980372150 title "Bortezomib Induced Peripheral Neuropathy: A Systematic Review of Phase III Trials" @default.
- W2980372150 doi "https://doi.org/10.1016/j.clml.2019.09.571" @default.
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