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- W2980387609 abstract "Significance The viral suppressor of RNA silencing P0 is known to target plant antiviral ARGONAUTE (AGO) proteins for degradation via an autophagy-related process. Here we utilized P0 to gain insight into the cellular degradation dynamics of AGO1, the major plant effector of RNA silencing. We revealed that P0 targets endoplasmic reticulum (ER)-associated AGO1 by inducing the formation of ER-related bodies that are delivered to the vacuole with both P0 and AGO1 as cargos. This process involves ATG8-interacting proteins 1 and 2 (ATI1 and ATI2) that interact with AGO1 and negatively regulate its transgene-silencing activity. Together, our results reveal a layer of ER-bound AGO1 posttranslational regulation that is manipulated by P0 to subvert plant antiviral defense." @default.
- W2980387609 created "2019-10-25" @default.
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- W2980387609 date "2019-10-18" @default.
- W2980387609 modified "2023-10-17" @default.
- W2980387609 title "The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1" @default.
- W2980387609 cites W1523693806 @default.
- W2980387609 cites W1860864010 @default.
- W2980387609 cites W1918329266 @default.
- W2980387609 cites W1968631483 @default.
- W2980387609 cites W1972999456 @default.
- W2980387609 cites W1974161033 @default.
- W2980387609 cites W1988031203 @default.
- W2980387609 cites W1991533918 @default.
- W2980387609 cites W1994823455 @default.
- W2980387609 cites W1998198759 @default.
- W2980387609 cites W2000831282 @default.
- W2980387609 cites W2001045944 @default.
- W2980387609 cites W2004271888 @default.
- W2980387609 cites W2004742914 @default.
- W2980387609 cites W2004764824 @default.
- W2980387609 cites W2005911581 @default.
- W2980387609 cites W2011518477 @default.
- W2980387609 cites W2012040176 @default.
- W2980387609 cites W2012356760 @default.
- W2980387609 cites W2015790286 @default.
- W2980387609 cites W2018172451 @default.
- W2980387609 cites W2021039359 @default.
- W2980387609 cites W2028652127 @default.
- W2980387609 cites W2035340311 @default.
- W2980387609 cites W2041403839 @default.
- W2980387609 cites W2045520458 @default.
- W2980387609 cites W2056782574 @default.
- W2980387609 cites W2059357290 @default.
- W2980387609 cites W2067775919 @default.
- W2980387609 cites W2074675420 @default.
- W2980387609 cites W2083761491 @default.
- W2980387609 cites W2094989185 @default.
- W2980387609 cites W2096842515 @default.
- W2980387609 cites W2102343982 @default.
- W2980387609 cites W2103764669 @default.
- W2980387609 cites W2111810018 @default.
- W2980387609 cites W2115676809 @default.
- W2980387609 cites W2118010772 @default.
- W2980387609 cites W2119421712 @default.
- W2980387609 cites W2121355028 @default.
- W2980387609 cites W2122135986 @default.
- W2980387609 cites W2127204797 @default.
- W2980387609 cites W2129395747 @default.
- W2980387609 cites W2130274188 @default.
- W2980387609 cites W2132947321 @default.
- W2980387609 cites W2134315298 @default.
- W2980387609 cites W2140786935 @default.
- W2980387609 cites W2141548533 @default.
- W2980387609 cites W2146253911 @default.
- W2980387609 cites W2150168624 @default.
- W2980387609 cites W2150183438 @default.
- W2980387609 cites W2151579372 @default.
- W2980387609 cites W2152389843 @default.
- W2980387609 cites W2153571621 @default.
- W2980387609 cites W2157096314 @default.
- W2980387609 cites W2157370528 @default.
- W2980387609 cites W2158178674 @default.
- W2980387609 cites W2161011558 @default.
- W2980387609 cites W2161381273 @default.
- W2980387609 cites W2195136000 @default.
- W2980387609 cites W2341889596 @default.
- W2980387609 cites W2534638628 @default.
- W2980387609 cites W2562009141 @default.
- W2980387609 cites W2579326722 @default.
- W2980387609 cites W2590407045 @default.
- W2980387609 cites W2592515550 @default.
- W2980387609 cites W2606510453 @default.
- W2980387609 cites W2619183404 @default.
- W2980387609 cites W2625178060 @default.
- W2980387609 cites W2769055835 @default.
- W2980387609 cites W2769524157 @default.
- W2980387609 cites W2787111906 @default.
- W2980387609 cites W2789450022 @default.
- W2980387609 cites W2794765381 @default.
- W2980387609 cites W2807316549 @default.
- W2980387609 cites W2885609324 @default.
- W2980387609 cites W2910143212 @default.