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- W2980387853 endingPage "93" @default.
- W2980387853 startingPage "72" @default.
- W2980387853 abstract "Nanoparticles (NPs) have been gaining prominence as delivery vehicles for modulating immune responses to improve treatments against cancer and autoimmune diseases, enhancing tissue regeneration capacity, and potentiating vaccination efficacy. Various engineering approaches have been extensively explored to control the NP physical and chemical properties including particle size, shape, surface charge, hydrophobicity, rigidity and surface targeting ligands to modulate immune responses. This review examines a specific set of physical and chemical characteristics of NPs that enable efficient delivery targeted to secondary lymphoid tissues, specifically the lymph nodes and immune cells. A critical analysis of the structure-property-function relationship will facilitate further efforts to engineer new NPs with unique functionalities, identify novel utilities, and improve the clinical translation of NP formulations for immunotherapy." @default.
- W2980387853 created "2019-10-25" @default.
- W2980387853 creator A5035996022 @default.
- W2980387853 creator A5039838088 @default.
- W2980387853 creator A5040144386 @default.
- W2980387853 creator A5053605155 @default.
- W2980387853 creator A5056721725 @default.
- W2980387853 creator A5069988863 @default.
- W2980387853 creator A5074628105 @default.
- W2980387853 date "2019-11-01" @default.
- W2980387853 modified "2023-10-13" @default.
- W2980387853 title "Physical and chemical profiles of nanoparticles for lymphatic targeting" @default.
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