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• W2980456921 endingPage "2958" @default.
• W2980456921 startingPage "2943" @default.
• W2980456921 abstract "Recent research has fueled a debate concerning the role of nicotine in the emergence of schizophrenia. The three main hypotheses are: (a) the self-medication effect, (b) the causal relationship hypothesis, or (c) the shared diathesis hypothesis. To explore this role, the study of nicotine consumption during the initial prodromal phase of schizophrenia offers important opportunities. In the present work, 10 relevant studies are reviewed, out of 727 retrieved citations, in order to address questions regarding the prevalence of smoking in the prodromal period, the time of smoking initiation, existing patterns of tobacco use in relation with the escalation of prodromal symptoms into first psychotic episode, and potential differences in symptomatology between smokers and nonsmokers. Even though there was considerable heterogeneity among studies, relevant findings are discussed. Prevalence of nicotine use during the prodromal period was reported to be 16.6-46%. Tobacco use was found to be taken up most often before or during the prodromal period of schizophrenia. Even though a protective role of smoking has been reported by one study, other studies report an increased risk for psychosis, with hazard ratios 2.77 (95% CI: 2.34-3.43) and 2.21 (95% CI: 1.11-4.42) for female and male heavy smokers (11-20 and >20 cigarettes/day), respectively. In a different study, the risk of onset was associated with the progressive use of cannabis and tobacco prior to onset, particularly with rapid escalation to the highest levels of use. Also, nicotine use in ultra high risk (UHR) for developing psychosis subjects is associated with elevated cognitive performance, namely better processing speed, visual learning, and spatial working memory. As a conclusion, it appears that evidence accumulates supporting a possible etiologic role of smoking, in the emergence of schizophrenia along with diverse effects on patients' symptomatology, already demonstrable at the prodromal phase. Future research employing better-defined criteria should further explore the patterns of use and effects of nicotine during the schizophrenia prodrome." @default.
• W2980456921 created "2019-10-25" @default.
• W2980456921 creator A5008260257 @default.
• W2980456921 creator A5016796399 @default.
• W2980456921 creator A5062355928 @default.
• W2980456921 creator A5073589249 @default.
• W2980456921 date "2019-10-01" @default.
• W2980456921 modified "2023-10-15" @default.
• W2980456921 title "<p>Nicotine consumption during the prodromal phase of schizophrenia – a review of the literature</p>" @default.
• W2980456921 cites W116781221 @default.
• W2980456921 cites W1487894289 @default.
• W2980456921 cites W1509604761 @default.
• W2980456921 cites W153652483 @default.
• W2980456921 cites W1702723615 @default.
• W2980456921 cites W1750202769 @default.
• W2980456921 cites W179281078 @default.
• W2980456921 cites W1924382915 @default.
• W2980456921 cites W1968593789 @default.
• W2980456921 cites W1969972941 @default.
• W2980456921 cites W1971993551 @default.
• W2980456921 cites W1973258071 @default.
• W2980456921 cites W1979692125 @default.
• W2980456921 cites W1981404361 @default.
• W2980456921 cites W1990043440 @default.
• W2980456921 cites W1990851347 @default.
• W2980456921 cites W1991374521 @default.
• W2980456921 cites W1997716145 @default.
• W2980456921 cites W1998319782 @default.
• W2980456921 cites W1999010778 @default.
• W2980456921 cites W2000010321 @default.
• W2980456921 cites W2002028713 @default.
• W2980456921 cites W2007231101 @default.
• W2980456921 cites W2008185869 @default.
• W2980456921 cites W2016732910 @default.
• W2980456921 cites W2023303929 @default.
• W2980456921 cites W2024654275 @default.
• W2980456921 cites W2025793608 @default.
• W2980456921 cites W2028087632 @default.
• W2980456921 cites W2029974021 @default.
• W2980456921 cites W2031520341 @default.
• W2980456921 cites W2036557906 @default.
• W2980456921 cites W2045061847 @default.
• W2980456921 cites W2047887517 @default.
• W2980456921 cites W2053163989 @default.
• W2980456921 cites W2053593733 @default.
• W2980456921 cites W2061139636 @default.
• W2980456921 cites W2062651377 @default.
• W2980456921 cites W2063985393 @default.
• W2980456921 cites W2063987229 @default.
• W2980456921 cites W2066363059 @default.
• W2980456921 cites W2074521340 @default.
• W2980456921 cites W2075233920 @default.
• W2980456921 cites W2078736215 @default.
• W2980456921 cites W2080255931 @default.
• W2980456921 cites W2087545154 @default.
• W2980456921 cites W2098392054 @default.
• W2980456921 cites W2101357408 @default.
• W2980456921 cites W2102461536 @default.
• W2980456921 cites W2102985017 @default.
• W2980456921 cites W2104378301 @default.
• W2980456921 cites W2105224023 @default.
• W2980456921 cites W2105347849 @default.
• W2980456921 cites W2106087454 @default.
• W2980456921 cites W2106770178 @default.
• W2980456921 cites W2110726313 @default.
• W2980456921 cites W2110846909 @default.
• W2980456921 cites W2111504432 @default.
• W2980456921 cites W2112443595 @default.
• W2980456921 cites W2114464807 @default.
• W2980456921 cites W2117575003 @default.
• W2980456921 cites W2118383875 @default.
• W2980456921 cites W2126345365 @default.
• W2980456921 cites W2129218722 @default.
• W2980456921 cites W2145602532 @default.
• W2980456921 cites W2145619523 @default.
• W2980456921 cites W2148898507 @default.
• W2980456921 cites W2162722107 @default.
• W2980456921 cites W2167813814 @default.
• W2980456921 cites W2170094083 @default.
• W2980456921 cites W2172000844 @default.
• W2980456921 cites W2179657949 @default.
• W2980456921 cites W2192428444 @default.
• W2980456921 cites W2232641565 @default.
• W2980456921 cites W2283021270 @default.
• W2980456921 cites W2301272550 @default.
• W2980456921 cites W2317320523 @default.
• W2980456921 cites W2344070856 @default.
• W2980456921 cites W2416746017 @default.
• W2980456921 cites W2417002138 @default.
• W2980456921 cites W2520553955 @default.
• W2980456921 cites W2577945917 @default.
• W2980456921 cites W2667130234 @default.
• W2980456921 cites W2755084841 @default.
• W2980456921 cites W276521613 @default.
• W2980456921 cites W2818417770 @default.
• W2980456921 cites W2892712968 @default.
• W2980456921 cites W2972751683 @default.
• W2980456921 cites W4210258384 @default.

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