FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980474897> ?p ?o ?g. }

• W2980474897 endingPage "7" @default.
• W2980474897 startingPage "1" @default.
• W2980474897 abstract "Debridement of the bone surface during a surgical fusion procedure initiates an injury response promoting a healing cascade of molecular mediators released over time. Autologous grafts offer natural scaffolding to fill the bone void and to provide local bone cells. Commercial bone grafting products such as allografts, synthetic bone mineral products, etc., are used to supplement or to replace autologous grafts by supporting osteoinductivity, osteoconductivity, and osteogenesis at the surgical site. To assure osteogenic potential, preservation of allogeneic cells with cryoprotectants has been developed to allow for long-term storage and thus delivery of viable bone cells to the surgical site. Dimethyl sulfoxide (DMSO) is an intracellular cryoprotectant commonly used because it provides good viability of the cells post-thaw. However, there is known cytotoxicity reported for DMSO when cells are stored above cryogenic temperatures. For most cellular bone graft products, the cryoprotectant is incorporated with the cells into the other mineralized bone and demineralized bone components. During thawing, the DMSO may not be sufficiently removed from allograft products compared to its use in a cell suspension where removal by washing and centrifugation is available. Therefore, both the allogeneic cell types in the bone grafting product and the local cell types at the bone grafting site could be affected as cytotoxicity varies by cell type and by DMSO content according to reported studies. Overcoming cytotoxicity may be an additional challenge in the formation of bone at a wound or surgical site. Other extracellular cryoprotectants have been explored as alternatives to DMSO which preserve without entering the cell membrane, thereby providing good cellular viability post-thaw and might abrogate the cytotoxicity concerns." @default.
• W2980474897 created "2019-10-25" @default.
• W2980474897 creator A5040642920 @default.
• W2980474897 creator A5055893512 @default.
• W2980474897 creator A5073513983 @default.
• W2980474897 creator A5090257289 @default.
• W2980474897 date "2019-10-16" @default.
• W2980474897 modified "2023-10-06" @default.
• W2980474897 title "Methods of Cryoprotectant Preservation: Allogeneic Cellular Bone Grafts and Potential Effects" @default.
• W2980474897 cites W13846868 @default.
• W2980474897 cites W164279958 @default.
• W2980474897 cites W1957534126 @default.
• W2980474897 cites W1968822620 @default.
• W2980474897 cites W1978560985 @default.
• W2980474897 cites W1996363939 @default.
• W2980474897 cites W2004337957 @default.
• W2980474897 cites W2025371271 @default.
• W2980474897 cites W2031046488 @default.
• W2980474897 cites W2036557984 @default.
• W2980474897 cites W2045865890 @default.
• W2980474897 cites W2046117322 @default.
• W2980474897 cites W2046178807 @default.
• W2980474897 cites W2053570594 @default.
• W2980474897 cites W2075558584 @default.
• W2980474897 cites W2077446889 @default.
• W2980474897 cites W2078221639 @default.
• W2980474897 cites W2086474578 @default.
• W2980474897 cites W2088513290 @default.
• W2980474897 cites W2089522209 @default.
• W2980474897 cites W2096832098 @default.
• W2980474897 cites W2104089107 @default.
• W2980474897 cites W2135647805 @default.
• W2980474897 cites W2140806962 @default.
• W2980474897 cites W2146738563 @default.
• W2980474897 cites W2157147749 @default.
• W2980474897 cites W2164988686 @default.
• W2980474897 cites W2169842119 @default.
• W2980474897 cites W2208962394 @default.
• W2980474897 cites W2322794129 @default.
• W2980474897 cites W2334795290 @default.
• W2980474897 cites W2414723847 @default.
• W2980474897 cites W2563099599 @default.
• W2980474897 cites W2568035168 @default.
• W2980474897 cites W2587573568 @default.
• W2980474897 cites W2608041883 @default.
• W2980474897 cites W2762731973 @default.
• W2980474897 cites W2767362487 @default.
• W2980474897 cites W2767404919 @default.
• W2980474897 cites W2802667050 @default.
• W2980474897 doi "https://doi.org/10.1155/2019/5025398" @default.
• W2980474897 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6817928" @default.
• W2980474897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31737666" @default.
• W2980474897 hasPublicationYear "2019" @default.
• W2980474897 type Work @default.
• W2980474897 sameAs 2980474897 @default.
• W2980474897 citedByCount "7" @default.
• W2980474897 countsByYear W29804748972021 @default.
• W2980474897 countsByYear W29804748972023 @default.
• W2980474897 crossrefType "journal-article" @default.
• W2980474897 hasAuthorship W2980474897A5040642920 @default.
• W2980474897 hasAuthorship W2980474897A5055893512 @default.
• W2980474897 hasAuthorship W2980474897A5073513983 @default.
• W2980474897 hasAuthorship W2980474897A5090257289 @default.
• W2980474897 hasBestOaLocation W29804748971 @default.
• W2980474897 hasConcept C141071460 @default.
• W2980474897 hasConcept C1491633281 @default.
• W2980474897 hasConcept C178790620 @default.
• W2980474897 hasConcept C179933525 @default.
• W2980474897 hasConcept C185592680 @default.
• W2980474897 hasConcept C196843134 @default.
• W2980474897 hasConcept C2776337968 @default.
• W2980474897 hasConcept C2778452553 @default.
• W2980474897 hasConcept C53227056 @default.
• W2980474897 hasConcept C55493867 @default.
• W2980474897 hasConcept C68528507 @default.
• W2980474897 hasConcept C71924100 @default.
• W2980474897 hasConcept C8337478 @default.
• W2980474897 hasConcept C86803240 @default.
• W2980474897 hasConcept C95444343 @default.
• W2980474897 hasConceptScore W2980474897C141071460 @default.
• W2980474897 hasConceptScore W2980474897C1491633281 @default.
• W2980474897 hasConceptScore W2980474897C178790620 @default.
• W2980474897 hasConceptScore W2980474897C179933525 @default.
• W2980474897 hasConceptScore W2980474897C185592680 @default.
• W2980474897 hasConceptScore W2980474897C196843134 @default.
• W2980474897 hasConceptScore W2980474897C2776337968 @default.
• W2980474897 hasConceptScore W2980474897C2778452553 @default.
• W2980474897 hasConceptScore W2980474897C53227056 @default.
• W2980474897 hasConceptScore W2980474897C55493867 @default.
• W2980474897 hasConceptScore W2980474897C68528507 @default.
• W2980474897 hasConceptScore W2980474897C71924100 @default.
• W2980474897 hasConceptScore W2980474897C8337478 @default.
• W2980474897 hasConceptScore W2980474897C86803240 @default.
• W2980474897 hasConceptScore W2980474897C95444343 @default.
• W2980474897 hasLocation W29804748971 @default.
• W2980474897 hasLocation W29804748972 @default.
• W2980474897 hasLocation W29804748973 @default.
• W2980474897 hasLocation W29804748974 @default.

• next