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- W2980477760 abstract "Background: Continuous evaluation of drug utilization in neonatal intensive care unit (NICU) is of great importance. It can promote rational use of drugs in neonates by providing feedback to clinicians about irrational use of medicines. Objective: To assess and quantify drug use pattern among neonates in NICU. Method: Prospective study was conducted in the NICU of tertiary care hospital for period of 1.5 years from January 2017 to June 2018. Case sheets of all neonates who were in NICU for more than 24 hours were analyzed according to WHO core prescribing indicators. Results: A total of 415 neonates were included. Average number of drugs per encounter was 7.5 ±5.75 (SD). Of a total of 3,118 prescribed drugs, most frequently prescribed class of drugs belonged to classes of J (antiinfectives for systemic use) followed by B (blood and blood forming organs) and A (alimentary tract and metabolism). Extremely low birth weight neonates and extremely preterm neonates received more number of drugs compared to other groups. Conclusion: Intravenous antiinfectives were the most prevalent used class of drugs. Inverse relationship between gestational age and birth weight with average number of drugs per encounter was observed. Safety profile of drugs prescribed for neonates is not fully established. So, further investigations and studies to optimize rational use of drugs in neonates and close monitoring of newborns to avoid potential risks is recommended" @default.
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- W2980477760 date "2019-01-01" @default.
- W2980477760 modified "2023-09-26" @default.
- W2980477760 title "Prospective study of drug utilization profile in neonatal intensive care unit of a tertiary care hospital" @default.
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