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- W2980493350 abstract "The hypothesis that semantic deficits in dementia may contribute in producing changes in eating preferences has never been experimentally investigated despite this association has been clinically observed. We administered tasks assessing semantic memory and the Appetite and Eating Habits Questionnaire (APEHQ) to 23 patients with dementia (behavioural frontotemporal dementia, primary progressive aphasia, and Alzheimer’s disease) and to 21 healthy controls. We used voxel‐based morphometry and diffusion tensor imaging to identify regions and white matter tracts of significant atrophy associated with the performance at the semantic tasks and the pathological scores at the APEHQ. We observed that the lower the patients’ scores at semantic tasks, the higher their changes in eating habits and preferences. Both semantic disorders and eating alterations correlated with atrophy in the temporal lobes and white matter tracts connecting the temporal lobe with frontal regions such as the arcuate fasciculus, the cingulum, and the inferior longitudinal fasciculus. These results confirm that semantic deficits underlie specific eating alterations in dementia patients." @default.
- W2980493350 created "2019-10-25" @default.
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- W2980493350 date "2019-10-16" @default.
- W2980493350 modified "2023-10-01" @default.
- W2980493350 title "Establishing links between abnormal eating behaviours and semantic deficits in dementia" @default.
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- W2980493350 doi "https://doi.org/10.1111/jnp.12195" @default.
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