Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980496431> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W2980496431 endingPage "366" @default.
- W2980496431 startingPage "360" @default.
- W2980496431 abstract "The neuromuscular junction(NMJ)is the synapse between a motor neuron and the skeletal muscle that is essential for muscle contraction. Impairments at the NMJ lead to neuromuscular-transmission pathologies characterized by fatigable muscle weakness. Muscle-specific receptor tyrosine kinase MuSK plays key roles in NMJ formation. Over the past decade, studies examining the NMJ formation signals have identified molecules involved in the signaling pathways and have promoted a better understanding of characteristic molecular mechanisms for MuSK activation. Unlike many other receptor tyrosine kinases, MuSK is regulated by the cytoplasmic activator Dok-7 in addition to the extracellular activator agrin. It is well established that all of these molecules are indispensable in the formation and maintenance of the NMJ. In this chapter, we review molecular signaling, particularly MuSK signaling, in the formation of the NMJ and the altered molecular signaling associated with neuromuscular disorders." @default.
- W2980496431 created "2019-10-25" @default.
- W2980496431 creator A5009692222 @default.
- W2980496431 creator A5068036440 @default.
- W2980496431 date "2018-03-08" @default.
- W2980496431 modified "2023-10-03" @default.
- W2980496431 title "[Homeostasis and Disorder of Musculoskeletal System.Molecular signaling and its pathogenic alterations in neuromuscular junction formation.]" @default.
- W2980496431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29512527" @default.
- W2980496431 hasPublicationYear "2018" @default.
- W2980496431 type Work @default.
- W2980496431 sameAs 2980496431 @default.
- W2980496431 citedByCount "0" @default.
- W2980496431 crossrefType "journal-article" @default.
- W2980496431 hasAuthorship W2980496431A5009692222 @default.
- W2980496431 hasAuthorship W2980496431A5068036440 @default.
- W2980496431 hasConcept C101544691 @default.
- W2980496431 hasConcept C134018914 @default.
- W2980496431 hasConcept C169760540 @default.
- W2980496431 hasConcept C170493617 @default.
- W2980496431 hasConcept C2777240379 @default.
- W2980496431 hasConcept C2779024559 @default.
- W2980496431 hasConcept C3020341438 @default.
- W2980496431 hasConcept C55493867 @default.
- W2980496431 hasConcept C62478195 @default.
- W2980496431 hasConcept C80161118 @default.
- W2980496431 hasConcept C86803240 @default.
- W2980496431 hasConcept C95444343 @default.
- W2980496431 hasConceptScore W2980496431C101544691 @default.
- W2980496431 hasConceptScore W2980496431C134018914 @default.
- W2980496431 hasConceptScore W2980496431C169760540 @default.
- W2980496431 hasConceptScore W2980496431C170493617 @default.
- W2980496431 hasConceptScore W2980496431C2777240379 @default.
- W2980496431 hasConceptScore W2980496431C2779024559 @default.
- W2980496431 hasConceptScore W2980496431C3020341438 @default.
- W2980496431 hasConceptScore W2980496431C55493867 @default.
- W2980496431 hasConceptScore W2980496431C62478195 @default.
- W2980496431 hasConceptScore W2980496431C80161118 @default.
- W2980496431 hasConceptScore W2980496431C86803240 @default.
- W2980496431 hasConceptScore W2980496431C95444343 @default.
- W2980496431 hasIssue "3" @default.
- W2980496431 hasLocation W29804964311 @default.
- W2980496431 hasOpenAccess W2980496431 @default.
- W2980496431 hasPrimaryLocation W29804964311 @default.
- W2980496431 hasRelatedWork W121445069 @default.
- W2980496431 hasRelatedWork W1990103645 @default.
- W2980496431 hasRelatedWork W2000220126 @default.
- W2980496431 hasRelatedWork W2046668530 @default.
- W2980496431 hasRelatedWork W2082745004 @default.
- W2980496431 hasRelatedWork W2137255104 @default.
- W2980496431 hasRelatedWork W2424958795 @default.
- W2980496431 hasRelatedWork W2594731224 @default.
- W2980496431 hasRelatedWork W573671015 @default.
- W2980496431 hasRelatedWork W2786129951 @default.
- W2980496431 hasVolume "28" @default.
- W2980496431 isParatext "false" @default.
- W2980496431 isRetracted "false" @default.
- W2980496431 magId "2980496431" @default.
- W2980496431 workType "article" @default.