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- W2980577680 abstract "Chalkophores are bacterial natural products that chelate and transport extracellular copper. The diisonitrile natural product SF2768 was first isolated from a Streptomyces species as an antifungal antibiotic and has more recently been characterized as a bacterial chalkophore and potential virulence factor. Herein, we report a modular synthesis of SF2768 and related acyclic analogues, allowing assignment of syn-stereochemistry across the central lactol ring. The copper-binding properties of these diisonitriles have also been studied." @default.
- W2980577680 created "2019-10-25" @default.
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- W2980577680 date "2019-10-21" @default.
- W2980577680 modified "2023-09-26" @default.
- W2980577680 title "Total Synthesis of the Bacterial Diisonitrile Chalkophore SF2768" @default.
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- W2980577680 doi "https://doi.org/10.1021/acs.orglett.9b03348" @default.
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