FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980590987> ?p ?o ?g. }

• W2980590987 abstract "Abstract Background To compare the clinical characteristics and treatment outcomes of microbiologically proven fungal keratitis between users and non-users of prior topical steroids (PS and NPS, respectively). Methods Eighty-three cases with microbiologically proven fungal keratitis between January 2000 and December 2016 were reviewed retrospectively. Diagnosis of fungal keratitis was made through potassium hydroxide smear, culture, PCR, or biopsy. Baseline epidemiology, predisposing factors, clinical characteristics, microbiological profiles, and treatment outcomes were evaluated and compared between the PS and NPS groups. Treatment failure was defined as any case with complications or requiring surgery. The risk factors for treatment failure were evaluated using multivariate logistic regression in the overall cohort. Results A total of 30 cases with PS group and 53 cases with NPS group were included. Of these, sixteen fungal isolates were identified in the PS group and 14 isolates in the NPS group. Candida was the most common organism in both groups (6 cases, respectively), while Aspergillus (4 cases) was found only in the PS group ( p = 0.103). No significant differences were observed in the mean age, sex, occupational distribution, epithelial defect size, hypopyon, and presenting best-corrected visual acuity (BCVA) between the two groups. Differences were observed between the PS and NPS groups in terms of previous ocular surface disease (OSD) (43.3% vs. 22.6%, p = 0.048) and deep infiltration (53.3% vs. 32.1%, p = 0.057). Regarding treatment outcomes, final BCVA < 0.1 (60% vs. 44.2%, p = 0.133), the use of voriconazole (topical 10% vs. 0%, p = 0.044; systemic 23.3% vs. 1.9%, p = 0.003), surgical intervention (43.3% vs. 20.8%, p = 0.029), and treatment failure (46.7% vs. 22.6%, p = 0.023) were more common in the PS group than in the NPS group. The significant risk factors for treatment failure were hypopyon (odds ratio [OR] 6.01, p = 0.005) and deep infiltration (OR 4.38, p = 0.013). Conclusions Previous OSD and deep infiltration were more common in the PS group compared to the NPS group. The PS group also experienced worse disease progression and treatment outcomes. These results highlight the need for paying attention to the use of steroids in clinical practice." @default.
• W2980590987 created "2019-10-25" @default.
• W2980590987 creator A5037451432 @default.
• W2980590987 creator A5040640298 @default.
• W2980590987 date "2019-10-16" @default.
• W2980590987 modified "2023-10-12" @default.
• W2980590987 title "Clinical analysis of microbiologically proven fungal keratitis according to prior topical steroid use: a retrospective study in South Korea" @default.
• W2980590987 cites W1573236707 @default.
• W2980590987 cites W1967363770 @default.
• W2980590987 cites W1969653015 @default.
• W2980590987 cites W1975231832 @default.
• W2980590987 cites W1983462777 @default.
• W2980590987 cites W1987972920 @default.
• W2980590987 cites W1998225942 @default.
• W2980590987 cites W2007487949 @default.
• W2980590987 cites W2009024442 @default.
• W2980590987 cites W2011051044 @default.
• W2980590987 cites W2012409544 @default.
• W2980590987 cites W2012487765 @default.
• W2980590987 cites W2019513344 @default.
• W2980590987 cites W2021005037 @default.
• W2980590987 cites W2053320686 @default.
• W2980590987 cites W2067086379 @default.
• W2980590987 cites W2074783218 @default.
• W2980590987 cites W2081618734 @default.
• W2980590987 cites W2093065084 @default.
• W2980590987 cites W2127880913 @default.
• W2980590987 cites W2135121307 @default.
• W2980590987 cites W2140886686 @default.
• W2980590987 cites W2142836222 @default.
• W2980590987 cites W2153077179 @default.
• W2980590987 cites W2157563352 @default.
• W2980590987 cites W2159936177 @default.
• W2980590987 cites W2160234801 @default.
• W2980590987 cites W2180471991 @default.
• W2980590987 cites W2318730529 @default.
• W2980590987 cites W2410757085 @default.
• W2980590987 cites W2411800135 @default.
• W2980590987 cites W2411860722 @default.
• W2980590987 cites W2417414159 @default.
• W2980590987 cites W4237275920 @default.
• W2980590987 doi "https://doi.org/10.1186/s12886-019-1212-0" @default.
• W2980590987 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6796396" @default.
• W2980590987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31619199" @default.
• W2980590987 hasPublicationYear "2019" @default.
• W2980590987 type Work @default.
• W2980590987 sameAs 2980590987 @default.
• W2980590987 citedByCount "18" @default.
• W2980590987 countsByYear W29805909872021 @default.
• W2980590987 countsByYear W29805909872022 @default.
• W2980590987 countsByYear W29805909872023 @default.
• W2980590987 crossrefType "journal-article" @default.
• W2980590987 hasAuthorship W2980590987A5037451432 @default.
• W2980590987 hasAuthorship W2980590987A5040640298 @default.
• W2980590987 hasBestOaLocation W29805909871 @default.
• W2980590987 hasConcept C126322002 @default.
• W2980590987 hasConcept C141071460 @default.
• W2980590987 hasConcept C16005928 @default.
• W2980590987 hasConcept C167135981 @default.
• W2980590987 hasConcept C2776079991 @default.
• W2980590987 hasConcept C2777520566 @default.
• W2980590987 hasConcept C2778257484 @default.
• W2980590987 hasConcept C2778560704 @default.
• W2980590987 hasConcept C2779548794 @default.
• W2980590987 hasConcept C2779629538 @default.
• W2980590987 hasConcept C2780690907 @default.
• W2980590987 hasConcept C2781403741 @default.
• W2980590987 hasConcept C71924100 @default.
• W2980590987 hasConceptScore W2980590987C126322002 @default.
• W2980590987 hasConceptScore W2980590987C141071460 @default.
• W2980590987 hasConceptScore W2980590987C16005928 @default.
• W2980590987 hasConceptScore W2980590987C167135981 @default.
• W2980590987 hasConceptScore W2980590987C2776079991 @default.
• W2980590987 hasConceptScore W2980590987C2777520566 @default.
• W2980590987 hasConceptScore W2980590987C2778257484 @default.
• W2980590987 hasConceptScore W2980590987C2778560704 @default.
• W2980590987 hasConceptScore W2980590987C2779548794 @default.
• W2980590987 hasConceptScore W2980590987C2779629538 @default.
• W2980590987 hasConceptScore W2980590987C2780690907 @default.
• W2980590987 hasConceptScore W2980590987C2781403741 @default.
• W2980590987 hasConceptScore W2980590987C71924100 @default.
• W2980590987 hasFunder F4320321380 @default.
• W2980590987 hasIssue "1" @default.
• W2980590987 hasLocation W29805909871 @default.
• W2980590987 hasLocation W29805909872 @default.
• W2980590987 hasLocation W29805909873 @default.
• W2980590987 hasLocation W29805909874 @default.
• W2980590987 hasLocation W29805909875 @default.
• W2980590987 hasLocation W29805909876 @default.
• W2980590987 hasOpenAccess W2980590987 @default.
• W2980590987 hasPrimaryLocation W29805909871 @default.
• W2980590987 hasRelatedWork W1964710480 @default.
• W2980590987 hasRelatedWork W2112693094 @default.
• W2980590987 hasRelatedWork W2114477944 @default.
• W2980590987 hasRelatedWork W2144347466 @default.
• W2980590987 hasRelatedWork W2147141118 @default.
• W2980590987 hasRelatedWork W2315477843 @default.
• W2980590987 hasRelatedWork W2510787437 @default.
• W2980590987 hasRelatedWork W2980590987 @default.
• W2980590987 hasRelatedWork W4236394077 @default.

• next