Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980751238> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2980751238 endingPage "261" @default.
- W2980751238 startingPage "256" @default.
- W2980751238 abstract "As dolutegravir (DTG), rilpivirine (RPV) and cobicistat affect creatinine, but not cystatin C, tubular transport or serum concentration, the aim of the study was to compare estimated glomerular filtration rates (eGFRs) calculated by means of a standard creatinine formula with those calculated by means of the cystatin C formula in patients receiving these drugs. This was a cross-sectional study of HIV-1 infected patients with eGFR <90 ml/min/1.73 m2 (CKD-EPI-creatinine formula) on-treatment with regimens including DTG, RVP or cobicistat; cystatin C was measured after the switch to these regimens. eGFR was calculated by means of the CKD-EPI formulas (CKD-EPI-creatinine: eGFRcrea; CKD-EPI-cystatin C: eGFRcyst). eGFRcyst was compared with the last eGFR assessed before (eGFRcrea pre) and after the switch (eGFRcrea post). The primary end-point of the study was the difference between eGFRcyst and eGFRcrea post. One hundred and twenty patients were included. eGFRcrea pre was 80 (70-92) ml/min/1.73 m2. eGFRcrea post was significantly lower than eGFRcyst (65 [59-75] vs. 80 [69-95] mL/ min/1.73m2; p<0.001); eGFRcyst did not differ from eGFRcrea pre (p=0.544). The difference between eGFRcyst and eGFRcrea post was not significantly different among regimen groups (p=0.056). In HIV-patients with reduced eGFR treated with DTG, RPV or cobicistat, measuring eGFR by means of the CKD-EPI cystatin C formula is probably more relevant." @default.
- W2980751238 created "2019-10-25" @default.
- W2980751238 creator A5001639111 @default.
- W2980751238 creator A5005264594 @default.
- W2980751238 creator A5032862205 @default.
- W2980751238 creator A5049035721 @default.
- W2980751238 creator A5087280168 @default.
- W2980751238 creator A5089618460 @default.
- W2980751238 date "2018-10-01" @default.
- W2980751238 modified "2023-09-28" @default.
- W2980751238 title "Glomerular filtration rate estimated by cystatin C formulas in HIV-1 patients treated with dolutegravir, rilpivirine or cobicistat." @default.
- W2980751238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30252923" @default.
- W2980751238 hasPublicationYear "2018" @default.
- W2980751238 type Work @default.
- W2980751238 sameAs 2980751238 @default.
- W2980751238 citedByCount "3" @default.
- W2980751238 countsByYear W29807512382020 @default.
- W2980751238 countsByYear W29807512382022 @default.
- W2980751238 crossrefType "journal-article" @default.
- W2980751238 hasAuthorship W2980751238A5001639111 @default.
- W2980751238 hasAuthorship W2980751238A5005264594 @default.
- W2980751238 hasAuthorship W2980751238A5032862205 @default.
- W2980751238 hasAuthorship W2980751238A5049035721 @default.
- W2980751238 hasAuthorship W2980751238A5087280168 @default.
- W2980751238 hasAuthorship W2980751238A5089618460 @default.
- W2980751238 hasConcept C126322002 @default.
- W2980751238 hasConcept C126894567 @default.
- W2980751238 hasConcept C142462285 @default.
- W2980751238 hasConcept C159047783 @default.
- W2980751238 hasConcept C159641895 @default.
- W2980751238 hasConcept C2777068322 @default.
- W2980751238 hasConcept C2778723075 @default.
- W2980751238 hasConcept C2779502633 @default.
- W2980751238 hasConcept C2779548226 @default.
- W2980751238 hasConcept C2780306776 @default.
- W2980751238 hasConcept C2780524789 @default.
- W2980751238 hasConcept C2781413609 @default.
- W2980751238 hasConcept C2993143319 @default.
- W2980751238 hasConcept C3013748606 @default.
- W2980751238 hasConcept C71924100 @default.
- W2980751238 hasConcept C90924648 @default.
- W2980751238 hasConcept C98274493 @default.
- W2980751238 hasConceptScore W2980751238C126322002 @default.
- W2980751238 hasConceptScore W2980751238C126894567 @default.
- W2980751238 hasConceptScore W2980751238C142462285 @default.
- W2980751238 hasConceptScore W2980751238C159047783 @default.
- W2980751238 hasConceptScore W2980751238C159641895 @default.
- W2980751238 hasConceptScore W2980751238C2777068322 @default.
- W2980751238 hasConceptScore W2980751238C2778723075 @default.
- W2980751238 hasConceptScore W2980751238C2779502633 @default.
- W2980751238 hasConceptScore W2980751238C2779548226 @default.
- W2980751238 hasConceptScore W2980751238C2780306776 @default.
- W2980751238 hasConceptScore W2980751238C2780524789 @default.
- W2980751238 hasConceptScore W2980751238C2781413609 @default.
- W2980751238 hasConceptScore W2980751238C2993143319 @default.
- W2980751238 hasConceptScore W2980751238C3013748606 @default.
- W2980751238 hasConceptScore W2980751238C71924100 @default.
- W2980751238 hasConceptScore W2980751238C90924648 @default.
- W2980751238 hasConceptScore W2980751238C98274493 @default.
- W2980751238 hasIssue "4" @default.
- W2980751238 hasLocation W29807512381 @default.
- W2980751238 hasOpenAccess W2980751238 @default.
- W2980751238 hasPrimaryLocation W29807512381 @default.
- W2980751238 hasRelatedWork W2172309875 @default.
- W2980751238 hasRelatedWork W2530393241 @default.
- W2980751238 hasRelatedWork W2685440764 @default.
- W2980751238 hasRelatedWork W2720472099 @default.
- W2980751238 hasRelatedWork W2800938943 @default.
- W2980751238 hasRelatedWork W2980751238 @default.
- W2980751238 hasRelatedWork W3100503434 @default.
- W2980751238 hasRelatedWork W3120525115 @default.
- W2980751238 hasRelatedWork W3124674627 @default.
- W2980751238 hasRelatedWork W4226212074 @default.
- W2980751238 hasVolume "41" @default.
- W2980751238 isParatext "false" @default.
- W2980751238 isRetracted "false" @default.
- W2980751238 magId "2980751238" @default.
- W2980751238 workType "article" @default.