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• W2980769520 abstract "SESSION TITLE: Clinical Outcomes in Cardiothoracic Surgery SESSION TYPE: Original Investigations PRESENTED ON: 10/21/2019 1:30 PM - 2:30 PM PURPOSE: Minimally invasive lung resection cause less trauma to tissues and hence improved recovery compared to open lung resection. Increasingly the robotic platform (RATS) has been used for minimally invasive lung resection and this has been shown to reduce peri-operative blood loss and better lymph node dissection compared to Video Assisted Thoracoscopic Surgery (VATS). Nevertheless there is an otherwise lack of evidence if RATS is better than VATS. We prospectively evaluated the impact on inflammatory cytokine levels in the immediate post-operative period between patients undergoing RATS and VATS. METHODS: Blood samples were obtained in the operating room prior to beginning of the surgery, 2 hours and 24 hours following surgery. The following specific cytokines and growth factors were measured EGF, IFN-g, IL1-a, IL1-b, IL-2, IL-4, IL-6, IL-8, IL-10, MCP-1. TNF-a, and VEGF, using Randox Biochip Cytokine Array I. All patients underwent intercostal blocks and incisional infiltration with liposomal bupivacaine during surgery. Additionally pain medicines were administered according to local protocol and the pain scores were recorded using a visual analog. Statistical analysis was performed using 2-way repeated measures ANOVA. RESULTS: Thirty patients undergoing minimally invasive lung resection (VATS=14, RATS=16) for malignancy were studied. There were 20 lobectomies (L), 3 segmentectomies (S) and 7 wedge resections (RATS=10L, 3S,3W; VATS=10L, 0S, 4W). The median age of the RATS group was higher (74.5±7.9 vs 65.5±6.5 years) the operative times were lower (165±25.4 mins vs 196±47.7 mins) and the length of hospital stay was lower (3 vs 3.5 days). IL-8, IL-10 and MCP-1 were significantly higher from pre-op values in both groups at 2 and 24 hours where as EGF was lower (p<0.001). CONCLUSIONS: RATS appear to cause less elevation of IL-6 levels in patients undergoing lung resections and this may translate to an advantage over VATS. CLINICAL IMPLICATIONS: Less inflammatory response may translate to better overall outcome following surgery including longer survival DISCLOSURES: No relevant relationships by Brett Curran, source=Web Response No relevant relationships by Walter Jeske, source=Admin input No relevant relationships by James Lubawski, source=Web Response No relevant relationships by Kostantinos Poulikidis, source=Web Response No relevant relationships by Adrian Rodrigues, source=Web Response No relevant relationships by Wickii Vigneswaran, source=Web Response No relevant relationships by Jeanine Walenga, source=Admin input" @default.
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• W2980769520 date "2019-10-01" @default.
• W2980769520 modified "2023-09-26" @default.
• W2980769520 title "ROBOTIC LUNG RESECTION CAUSES LESS INFLAMMATORY RESPONSE COMPARED TO VIDEO-ASSISTED THORACOSCOPIC LUNG RESECTION" @default.
• W2980769520 doi "https://doi.org/10.1016/j.chest.2019.08.211" @default.
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