FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980822018> ?p ?o ?g. }

• W2980822018 endingPage "301" @default.
• W2980822018 startingPage "293" @default.
• W2980822018 abstract "Fibromyalgia is a chronic condition characterized by widespread pain, fatigue, and sleep disturbances that affects approximately 2% to 4% of the adult population in the United States, with minimal real-world data related to the use of medications and associated dosages for this condition.To analyze the real-world dosing patterns of the 3 medications approved by the US Food and Drug Administration for fibromyalgia-pregabalin, duloxetine, and milnacipran.Using QuintilesIMS' (now IQVIA) electronic medical record data linked to administrative claims, we identified adults with fibromyalgia who were newly prescribed pregabalin, duloxetine, or milnacipran between January 1, 2006, and December 31, 2014. We summarized and compared the starting and maximum doses with United States prescribing information (USPI) dosing recommendations.In all, 1043 patients who were receiving pregabalin, 1281 receiving duloxetine, and 326 patients receiving milnacipran with similar age and comorbidity profiles were included in the study. The mean starting dose was 176 mg daily, 56 mg daily, and 95 mg daily for pregabalin, duloxetine, and milnacipran, respectively. More patients receiving pregabalin (35%) had a starting dose lower than recommended compared with patients receiving duloxetine (7%) or milnacipran (17%; P <.0001). Of the patients who received pregabalin, 27% had USPI-recommended maintenance dosing versus 91% of patients who received duloxetine and 80% who received milnacipran (P <.0001). The mean duration of treatment was longer for duloxetine (205 days; P <.0001) than for pregabalin (167 days) and milnacipran (167 days). The duration of using the maximum dose of each medication as a percentage of the total time of medication use was 77% for pregabalin, 84% for duloxetine, and 90% for milnacipran (P <.0001).Patients using pregabalin were the most likely of the 3 cohorts to receive lower than label-recommended starting doses and the least likely to receive the recommended maintenance doses during follow-up compared with those receiving duloxetine or milnacipran. Real-world prescribing patterns indicate that factors other than label recommendations may be influencing prescribed dosing." @default.
• W2980822018 created "2019-10-25" @default.
• W2980822018 creator A5030922228 @default.
• W2980822018 creator A5031823808 @default.
• W2980822018 creator A5039228092 @default.
• W2980822018 creator A5043134141 @default.
• W2980822018 creator A5043812704 @default.
• W2980822018 creator A5063653665 @default.
• W2980822018 date "2018-09-01" @default.
• W2980822018 modified "2023-10-10" @default.
• W2980822018 title "Analysis of Real-World Dosing Patterns for the 3 FDA-Approved Medications in the Treatment of Fibromyalgia." @default.
• W2980822018 cites W1580240033 @default.
• W2980822018 cites W1706551410 @default.
• W2980822018 cites W2000445173 @default.
• W2980822018 cites W2001923653 @default.
• W2980822018 cites W2022815318 @default.
• W2980822018 cites W2034403347 @default.
• W2980822018 cites W2083048810 @default.
• W2980822018 cites W2115847005 @default.
• W2980822018 cites W2136445221 @default.
• W2980822018 cites W2143549688 @default.
• W2980822018 cites W2149594634 @default.
• W2980822018 cites W2151868503 @default.
• W2980822018 cites W2153024655 @default.
• W2980822018 cites W2160820922 @default.
• W2980822018 cites W2163576272 @default.
• W2980822018 cites W2287282505 @default.
• W2980822018 cites W2980822018 @default.
• W2980822018 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6207316" @default.
• W2980822018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30464796" @default.
• W2980822018 hasPublicationYear "2018" @default.
• W2980822018 type Work @default.
• W2980822018 sameAs 2980822018 @default.
• W2980822018 citedByCount "3" @default.
• W2980822018 countsByYear W29808220182020 @default.
• W2980822018 crossrefType "journal-article" @default.
• W2980822018 hasAuthorship W2980822018A5030922228 @default.
• W2980822018 hasAuthorship W2980822018A5031823808 @default.
• W2980822018 hasAuthorship W2980822018A5039228092 @default.
• W2980822018 hasAuthorship W2980822018A5043134141 @default.
• W2980822018 hasAuthorship W2980822018A5043812704 @default.
• W2980822018 hasAuthorship W2980822018A5063653665 @default.
• W2980822018 hasConcept C126322002 @default.
• W2980822018 hasConcept C142724271 @default.
• W2980822018 hasConcept C204787440 @default.
• W2980822018 hasConcept C2776468701 @default.
• W2980822018 hasConcept C2777288759 @default.
• W2980822018 hasConcept C2777831278 @default.
• W2980822018 hasConcept C2779177272 @default.
• W2980822018 hasConcept C2780199185 @default.
• W2980822018 hasConcept C2780764818 @default.
• W2980822018 hasConcept C2781161787 @default.
• W2980822018 hasConcept C42219234 @default.
• W2980822018 hasConcept C71924100 @default.
• W2980822018 hasConceptScore W2980822018C126322002 @default.
• W2980822018 hasConceptScore W2980822018C142724271 @default.
• W2980822018 hasConceptScore W2980822018C204787440 @default.
• W2980822018 hasConceptScore W2980822018C2776468701 @default.
• W2980822018 hasConceptScore W2980822018C2777288759 @default.
• W2980822018 hasConceptScore W2980822018C2777831278 @default.
• W2980822018 hasConceptScore W2980822018C2779177272 @default.
• W2980822018 hasConceptScore W2980822018C2780199185 @default.
• W2980822018 hasConceptScore W2980822018C2780764818 @default.
• W2980822018 hasConceptScore W2980822018C2781161787 @default.
• W2980822018 hasConceptScore W2980822018C42219234 @default.
• W2980822018 hasConceptScore W2980822018C71924100 @default.
• W2980822018 hasIssue "6" @default.
• W2980822018 hasLocation W29808220181 @default.
• W2980822018 hasOpenAccess W2980822018 @default.
• W2980822018 hasPrimaryLocation W29808220181 @default.
• W2980822018 hasRelatedWork W116643785 @default.
• W2980822018 hasRelatedWork W1980290594 @default.
• W2980822018 hasRelatedWork W2060362303 @default.
• W2980822018 hasRelatedWork W2134516534 @default.
• W2980822018 hasRelatedWork W2320075070 @default.
• W2980822018 hasRelatedWork W2329258423 @default.
• W2980822018 hasRelatedWork W2980822018 @default.
• W2980822018 hasRelatedWork W4213305982 @default.
• W2980822018 hasRelatedWork W88055367 @default.
• W2980822018 hasRelatedWork W2093165528 @default.
• W2980822018 hasVolume "11" @default.
• W2980822018 isParatext "false" @default.
• W2980822018 isRetracted "false" @default.
• W2980822018 magId "2980822018" @default.
• W2980822018 workType "article" @default.