FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980920133> ?p ?o ?g. }

• W2980920133 endingPage "115478" @default.
• W2980920133 startingPage "115478" @default.
• W2980920133 abstract "The clinical use of many chemotherapeutic drugs is considerably greatly limited due to their serious side effects. This problem can be solved by using a low-toxic or nontoxic drug carrier that exhibits excellent performance in entrapping chemotherapeutic drugs. Accordingly, β-cyclodextrin-PEG-guanosine (β-CD-PEG-G) molecule was first synthesized. The molecules can self-assemble into negatively charged spherical aggregates (called β-CD-PEG-G aggregates) that can stably exist in an aqueous solution and entrap doxorubicin (Dox) to form β-CD-PEG-G-Dox nanomedicine. Dox encapsulation efficiency is approximately 79 ± 6.3%. Dox from β-CD-PEG-G-Dox nanomedicine exhibits sustained release and pH responsiveness. Cell and animal experiments showed that β-CD-PEG-G-Dox nanomedicine could effectively induce cancer cell apoptosis to exert antitumor activity. Unexpectively, the animal experiment and tissue sections demonstrated that β-CD-PEG-G aggregates exhibit certain antitumor activity that could delay the tumor growth. Therefore, the β-CD-PEG-G molecule has high potential as a drug carrier candidate." @default.
• W2980920133 created "2019-10-25" @default.
• W2980920133 creator A5003721576 @default.
• W2980920133 creator A5012677271 @default.
• W2980920133 creator A5017656312 @default.
• W2980920133 creator A5017812494 @default.
• W2980920133 creator A5025024898 @default.
• W2980920133 creator A5045481641 @default.
• W2980920133 creator A5049559559 @default.
• W2980920133 date "2020-02-01" @default.
• W2980920133 modified "2023-09-24" @default.
• W2980920133 title "Synthesis of β-cyclodextrin-PEG-G molecules to delay tumor growth and application of β-cyclodextrin-PEG-G aggregates as drug carrier" @default.
• W2980920133 cites W1963719931 @default.
• W2980920133 cites W1967984219 @default.
• W2980920133 cites W1973116782 @default.
• W2980920133 cites W1983338915 @default.
• W2980920133 cites W1985858988 @default.
• W2980920133 cites W1991376557 @default.
• W2980920133 cites W2074544404 @default.
• W2980920133 cites W2093495159 @default.
• W2980920133 cites W2165884308 @default.
• W2980920133 cites W2168824554 @default.
• W2980920133 cites W2440016573 @default.
• W2980920133 cites W2491293312 @default.
• W2980920133 cites W2557331116 @default.
• W2980920133 cites W2591094479 @default.
• W2980920133 cites W2783909074 @default.
• W2980920133 cites W2886998885 @default.
• W2980920133 cites W2889344199 @default.
• W2980920133 cites W2893882436 @default.
• W2980920133 cites W2912184964 @default.
• W2980920133 doi "https://doi.org/10.1016/j.carbpol.2019.115478" @default.
• W2980920133 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31826440" @default.
• W2980920133 hasPublicationYear "2020" @default.
• W2980920133 type Work @default.
• W2980920133 sameAs 2980920133 @default.
• W2980920133 citedByCount "13" @default.
• W2980920133 countsByYear W29809201332020 @default.
• W2980920133 countsByYear W29809201332021 @default.
• W2980920133 countsByYear W29809201332022 @default.
• W2980920133 countsByYear W29809201332023 @default.
• W2980920133 crossrefType "journal-article" @default.
• W2980920133 hasAuthorship W2980920133A5003721576 @default.
• W2980920133 hasAuthorship W2980920133A5012677271 @default.
• W2980920133 hasAuthorship W2980920133A5017656312 @default.
• W2980920133 hasAuthorship W2980920133A5017812494 @default.
• W2980920133 hasAuthorship W2980920133A5025024898 @default.
• W2980920133 hasAuthorship W2980920133A5045481641 @default.
• W2980920133 hasAuthorship W2980920133A5049559559 @default.
• W2980920133 hasConcept C10138342 @default.
• W2980920133 hasConcept C12554922 @default.
• W2980920133 hasConcept C13245373 @default.
• W2980920133 hasConcept C141071460 @default.
• W2980920133 hasConcept C15083742 @default.
• W2980920133 hasConcept C155672457 @default.
• W2980920133 hasConcept C162324750 @default.
• W2980920133 hasConcept C171250308 @default.
• W2980920133 hasConcept C178790620 @default.
• W2980920133 hasConcept C184651966 @default.
• W2980920133 hasConcept C185592680 @default.
• W2980920133 hasConcept C192562407 @default.
• W2980920133 hasConcept C21951064 @default.
• W2980920133 hasConcept C2776694085 @default.
• W2980920133 hasConcept C2779433975 @default.
• W2980920133 hasConcept C2779820397 @default.
• W2980920133 hasConcept C2780035454 @default.
• W2980920133 hasConcept C2781303535 @default.
• W2980920133 hasConcept C54400483 @default.
• W2980920133 hasConcept C55493867 @default.
• W2980920133 hasConcept C71924100 @default.
• W2980920133 hasConcept C86803240 @default.
• W2980920133 hasConcept C98274493 @default.
• W2980920133 hasConceptScore W2980920133C10138342 @default.
• W2980920133 hasConceptScore W2980920133C12554922 @default.
• W2980920133 hasConceptScore W2980920133C13245373 @default.
• W2980920133 hasConceptScore W2980920133C141071460 @default.
• W2980920133 hasConceptScore W2980920133C15083742 @default.
• W2980920133 hasConceptScore W2980920133C155672457 @default.
• W2980920133 hasConceptScore W2980920133C162324750 @default.
• W2980920133 hasConceptScore W2980920133C171250308 @default.
• W2980920133 hasConceptScore W2980920133C178790620 @default.
• W2980920133 hasConceptScore W2980920133C184651966 @default.
• W2980920133 hasConceptScore W2980920133C185592680 @default.
• W2980920133 hasConceptScore W2980920133C192562407 @default.
• W2980920133 hasConceptScore W2980920133C21951064 @default.
• W2980920133 hasConceptScore W2980920133C2776694085 @default.
• W2980920133 hasConceptScore W2980920133C2779433975 @default.
• W2980920133 hasConceptScore W2980920133C2779820397 @default.
• W2980920133 hasConceptScore W2980920133C2780035454 @default.
• W2980920133 hasConceptScore W2980920133C2781303535 @default.
• W2980920133 hasConceptScore W2980920133C54400483 @default.
• W2980920133 hasConceptScore W2980920133C55493867 @default.
• W2980920133 hasConceptScore W2980920133C71924100 @default.
• W2980920133 hasConceptScore W2980920133C86803240 @default.
• W2980920133 hasConceptScore W2980920133C98274493 @default.
• W2980920133 hasFunder F4320335983 @default.
• W2980920133 hasLocation W29809201331 @default.
• W2980920133 hasLocation W29809201332 @default.

• next