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• W2980923690 abstract "Alzheimer's disease (AD) affects the memory and cognitive function of approximately 5.7 million Americans. Early detection subsequently allows for earlier treatment and improves outcomes. Current in-clinic assessments are cumbersome for patients; thus, field assessments for home-use are needed to increase accessibility and reduce barriers for testing. Thus, the purpose of the current investigation was to determine the ability of a 5-minute visual paired comparison (VPC) task using an easily accessible web-cam to predict cognitive state among adults. Adults 18 years and older participated in the present investigation. Upon arrival to the laboratory, each participant signed a written informed consent document, completed a demographic questionnaire, the Montreal Cognitive Assessment (MoCA), and VPC task. Participants with MoCA scores ≥ 26 were classified as cognitively intact (CIN), whereas, participants with MoCA scores < 26 were classified as cognitively impaired (CIM). VPC calculates the relative time spent gazing at novel versus previously viewed images via web-cam. Results were analyzed using logistic regression with MoCA as the dependent variable (CIM vs. CIN) and VPC score, age, sex, and education used as the predictor variables. Fifty-one (43 CIN; 8 CIM) participants completed all assessments. Average age was 55.9 ± 26.8 years (CIN: 50.6 ± 27.0 years; CIM: 78.6 ± 6.4 years). Individuals in the CIM group scored 66.64 ± 12.9%; the CIN group scored 83.84 ± 7.77% on the VPC task. The model explained 55% of the variance of the MoCA cognitive classification and correctly identified 90% (95% of CIN group; 63% of CIM group) of adults into either the CIN or the CIM category (p < .001). It should be noted in the present model, only VPC score was a significant predictor of MoCA classification (p < .001). Results from the present investigation suggest VPC is a valid screening tool for cognitive impairment. VPC may be a viable alternative when compared to other assessment tools and can be performed outside a clinician's office. This type of assessment significantly increases the scalability of the screening modality, allowing the general population the ability to assess and track preclinical changes in cognition over time." @default.
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• W2980923690 date "2019-07-01" @default.
• W2980923690 modified "2023-09-28" @default.
• W2980923690 title "P4-539: EYE TRACKING DURING A VISUAL PAIRED COMPARISON TASK PREDICTS COGNITION" @default.
• W2980923690 doi "https://doi.org/10.1016/j.jalz.2019.08.086" @default.
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