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- W2980929802 abstract "The ongoing obesity epidemic places about a third of American youth at risk for developing obesity-related insulin resistance. This is manifested by reduced multiorgan effects of insulin, leading to elevated insulin concentrations and, in some cases, inappropriately elevated glucose and lipid concentrations. Many risk factors for insulin resistance—including genetics, epigenetics, obesity, diet, and lifestyle—are in common between adolescents and adults. However, adolescents have a unique risk factor in the physiologic insulin resistance of puberty, which along with obesity can pose a “double hit” to the beta-cell, causing increased burden for insulin secretion." @default.
- W2980929802 created "2019-10-25" @default.
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- W2980929802 date "2019-10-15" @default.
- W2980929802 modified "2023-09-26" @default.
- W2980929802 title "Clinical Manifestations of Insulin Resistance in Youth" @default.
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- W2980929802 doi "https://doi.org/10.1007/978-3-030-25057-7_1" @default.
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