FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2980932010> ?p ?o ?g. }

• W2980932010 endingPage "827" @default.
• W2980932010 startingPage "827" @default.
• W2980932010 abstract "Captive breeding has been used as an effective approach to protecting endangered animals but its effect on the gut microbiome and the conservation status of these species is largely unknown. The giant panda is a flagship species for the conservation of wildlife. With integrated efforts including captive breeding, this species has been recently upgraded from “endangered” to “vulnerable” (IUCN 2016). Since a large proportion (21.8%) of their global population is still captive, it is critical to understand how captivity changes the gut microbiome of these pandas and how such alterations to the microbiome might affect their future fitness and potential impact on the ecosystem after release into the wild. Here, we use 16S rRNA (ribosomal RNA) marker gene sequencing and shotgun metagenomics sequencing to demonstrate that the fecal microbiomes differ substantially between wild and captive giant pandas. Fecal microbiome diversity was significantly lower in captive pandas, as was the diversity of functional genes. Additionally, captive pandas have reduced functional potential for cellulose degradation but enriched metabolic pathways for starch metabolism, indicating that they may not adapt to a wild diet after being released into the wild since a major component of their diet in the wild will be bamboo. Most significantly, we observed a significantly higher level of amylase activity but a lower level of cellulase activity in captive giant panda feces than those of wild giant pandas, shown by an in vitro experimental assay. Furthermore, antibiotic resistance genes and virulence factors, as well as heavy metal tolerance genes were enriched in the microbiomes of captive pandas, which raises a great concern of spreading these genes to other wild animals and ecosystems when they are released into a wild environment. Our results clearly show that captivity has altered the giant panda microbiome, which could have unintended negative consequences on their adaptability and the ecosystem during the reintroduction of giant pandas into the wild." @default.
• W2980932010 created "2019-10-25" @default.
• W2980932010 creator A5009458526 @default.
• W2980932010 creator A5023504231 @default.
• W2980932010 creator A5027830539 @default.
• W2980932010 creator A5033649488 @default.
• W2980932010 creator A5046720969 @default.
• W2980932010 creator A5052692974 @default.
• W2980932010 creator A5060002817 @default.
• W2980932010 creator A5063743102 @default.
• W2980932010 creator A5066997081 @default.
• W2980932010 date "2019-10-20" @default.
• W2980932010 modified "2023-10-14" @default.
• W2980932010 title "Comparative Study of Gut Microbiota in Wild and Captive Giant Pandas (Ailuropoda melanoleuca)" @default.
• W2980932010 cites W1557515632 @default.
• W2980932010 cites W1568043102 @default.
• W2980932010 cites W1724616540 @default.
• W2980932010 cites W1963743386 @default.
• W2980932010 cites W1989348205 @default.
• W2980932010 cites W2008274231 @default.
• W2980932010 cites W2009674410 @default.
• W2980932010 cites W2026299543 @default.
• W2980932010 cites W2027184506 @default.
• W2980932010 cites W2033527425 @default.
• W2980932010 cites W2036897871 @default.
• W2980932010 cites W2052633548 @default.
• W2980932010 cites W2072970694 @default.
• W2980932010 cites W2078211865 @default.
• W2980932010 cites W2085487818 @default.
• W2980932010 cites W2089212356 @default.
• W2980932010 cites W2103441770 @default.
• W2980932010 cites W2108234281 @default.
• W2980932010 cites W2108929776 @default.
• W2980932010 cites W2112874908 @default.
• W2980932010 cites W2117457769 @default.
• W2980932010 cites W2117582473 @default.
• W2980932010 cites W2127059753 @default.
• W2980932010 cites W2131271579 @default.
• W2980932010 cites W2133579817 @default.
• W2980932010 cites W2133856765 @default.
• W2980932010 cites W2135621733 @default.
• W2980932010 cites W2136720095 @default.
• W2980932010 cites W2136793248 @default.
• W2980932010 cites W2136879569 @default.
• W2980932010 cites W2141920662 @default.
• W2980932010 cites W2144568881 @default.
• W2980932010 cites W2149559438 @default.
• W2980932010 cites W2155367962 @default.
• W2980932010 cites W2156701707 @default.
• W2980932010 cites W2159946869 @default.
• W2980932010 cites W2160452746 @default.
• W2980932010 cites W2170747616 @default.
• W2980932010 cites W2173913502 @default.
• W2980932010 cites W2338786641 @default.
• W2980932010 cites W2343175653 @default.
• W2980932010 cites W2346000380 @default.
• W2980932010 cites W2484230073 @default.
• W2980932010 cites W2502699018 @default.
• W2980932010 cites W2511347330 @default.
• W2980932010 cites W2518810629 @default.
• W2980932010 cites W2528511189 @default.
• W2980932010 cites W2543813668 @default.
• W2980932010 cites W2556521897 @default.
• W2980932010 cites W2562034617 @default.
• W2980932010 cites W2563315795 @default.
• W2980932010 cites W2617829877 @default.
• W2980932010 cites W2734758444 @default.
• W2980932010 cites W2743115441 @default.
• W2980932010 cites W2767431605 @default.
• W2980932010 cites W2768753541 @default.
• W2980932010 cites W2768975905 @default.
• W2980932010 cites W2790162428 @default.
• W2980932010 cites W2794287016 @default.
• W2980932010 cites W2802758762 @default.
• W2980932010 cites W2806776702 @default.
• W2980932010 cites W2908387490 @default.
• W2980932010 cites W2910672108 @default.
• W2980932010 cites W2911964244 @default.
• W2980932010 cites W2914065622 @default.
• W2980932010 cites W2918998295 @default.
• W2980932010 cites W2942676572 @default.
• W2980932010 cites W2946855393 @default.
• W2980932010 cites W2961924668 @default.
• W2980932010 doi "https://doi.org/10.3390/genes10100827" @default.
• W2980932010 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6826394" @default.
• W2980932010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31635158" @default.
• W2980932010 hasPublicationYear "2019" @default.
• W2980932010 type Work @default.
• W2980932010 sameAs 2980932010 @default.
• W2980932010 citedByCount "54" @default.
• W2980932010 countsByYear W29809320102020 @default.
• W2980932010 countsByYear W29809320102021 @default.
• W2980932010 countsByYear W29809320102022 @default.
• W2980932010 countsByYear W29809320102023 @default.
• W2980932010 crossrefType "journal-article" @default.
• W2980932010 hasAuthorship W2980932010A5009458526 @default.
• W2980932010 hasAuthorship W2980932010A5023504231 @default.
• W2980932010 hasAuthorship W2980932010A5027830539 @default.

• next