Matches in SemOpenAlex for { <https://semopenalex.org/work/W2981034715> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2981034715 abstract "Sundown syndrome (SS) in patients with Alzheimer's disease (AD) is characterized by aggravation of behavioral problems at sunset. Disturbance of the circadian rhythm, a possible cause of SS, also facilitates amyloidopathy and reduces sleep quality. However, the associations of SS with amyloidopathy and sleep quality remain unclear. We aimed to investigate the prevalence of SS in patients with AD, the association between SS and APOE ε4 carrier, representing an enhanced amyloid pathology, and the relationship between SS and sleep quality in AD. We included 104 patients with late-onset AD and known APOE genotype. All participants underwent a structured interview via informant-based questionnaires to assess sleep quality and the presence of SS. Binary logistic regression analysis was performed to determine odds ratios (ORs) of APOE ε4 carrier and parameters of sleep quality for SS. The prevalence of SS in AD was 27.8% (n = 29). Patients with SS were significantly more likely to be APOE ε4 carriers and to have rapid eye movement sleep behavior disorder (RBD) and a higher Clinical Dementia Rating (CDR) score compared to those without SS. In the multivariate regression analysis, APOE ε4 carrier (OR 3.158, CI 1.022–9.758), RBD (OR 2.166, CI 1.073–4.371), and higher CDR score (OR 2.453, CI 1.084–5.550) showed increased risk for SS. The prevalence of SS in patients with AD was 27.8%. The presence of the APOE ε4 allele, RBD, and more severe dementia increase the risk of SS in AD." @default.
- W2981034715 created "2019-10-25" @default.
- W2981034715 creator A5001679413 @default.
- W2981034715 creator A5010892800 @default.
- W2981034715 creator A5018017627 @default.
- W2981034715 creator A5028978854 @default.
- W2981034715 creator A5046271018 @default.
- W2981034715 creator A5047005390 @default.
- W2981034715 date "2019-07-01" @default.
- W2981034715 modified "2023-09-27" @default.
- W2981034715 title "P1-324: APOE ε4 AND REM SLEEP BEHAVIOR DISORDER AS RISK FACTORS FOR SUNDOWN SYNDROME IN ALZHEIMER'S DISEASE" @default.
- W2981034715 doi "https://doi.org/10.1016/j.jalz.2019.06.879" @default.
- W2981034715 hasPublicationYear "2019" @default.
- W2981034715 type Work @default.
- W2981034715 sameAs 2981034715 @default.
- W2981034715 citedByCount "0" @default.
- W2981034715 crossrefType "journal-article" @default.
- W2981034715 hasAuthorship W2981034715A5001679413 @default.
- W2981034715 hasAuthorship W2981034715A5010892800 @default.
- W2981034715 hasAuthorship W2981034715A5018017627 @default.
- W2981034715 hasAuthorship W2981034715A5028978854 @default.
- W2981034715 hasAuthorship W2981034715A5046271018 @default.
- W2981034715 hasAuthorship W2981034715A5047005390 @default.
- W2981034715 hasBestOaLocation W29810347151 @default.
- W2981034715 hasConcept C111919701 @default.
- W2981034715 hasConcept C118552586 @default.
- W2981034715 hasConcept C121446783 @default.
- W2981034715 hasConcept C126322002 @default.
- W2981034715 hasConcept C1513209611 @default.
- W2981034715 hasConcept C151956035 @default.
- W2981034715 hasConcept C156957248 @default.
- W2981034715 hasConcept C15744967 @default.
- W2981034715 hasConcept C2775841894 @default.
- W2981034715 hasConcept C2776132596 @default.
- W2981034715 hasConcept C2776245837 @default.
- W2981034715 hasConcept C2779134260 @default.
- W2981034715 hasConcept C2779483572 @default.
- W2981034715 hasConcept C2779734285 @default.
- W2981034715 hasConcept C2780906993 @default.
- W2981034715 hasConcept C2781210498 @default.
- W2981034715 hasConcept C2983189541 @default.
- W2981034715 hasConcept C41008148 @default.
- W2981034715 hasConcept C57089818 @default.
- W2981034715 hasConcept C71924100 @default.
- W2981034715 hasConceptScore W2981034715C111919701 @default.
- W2981034715 hasConceptScore W2981034715C118552586 @default.
- W2981034715 hasConceptScore W2981034715C121446783 @default.
- W2981034715 hasConceptScore W2981034715C126322002 @default.
- W2981034715 hasConceptScore W2981034715C1513209611 @default.
- W2981034715 hasConceptScore W2981034715C151956035 @default.
- W2981034715 hasConceptScore W2981034715C156957248 @default.
- W2981034715 hasConceptScore W2981034715C15744967 @default.
- W2981034715 hasConceptScore W2981034715C2775841894 @default.
- W2981034715 hasConceptScore W2981034715C2776132596 @default.
- W2981034715 hasConceptScore W2981034715C2776245837 @default.
- W2981034715 hasConceptScore W2981034715C2779134260 @default.
- W2981034715 hasConceptScore W2981034715C2779483572 @default.
- W2981034715 hasConceptScore W2981034715C2779734285 @default.
- W2981034715 hasConceptScore W2981034715C2780906993 @default.
- W2981034715 hasConceptScore W2981034715C2781210498 @default.
- W2981034715 hasConceptScore W2981034715C2983189541 @default.
- W2981034715 hasConceptScore W2981034715C41008148 @default.
- W2981034715 hasConceptScore W2981034715C57089818 @default.
- W2981034715 hasConceptScore W2981034715C71924100 @default.
- W2981034715 hasIssue "7S_Part_7" @default.
- W2981034715 hasLocation W29810347151 @default.
- W2981034715 hasOpenAccess W2981034715 @default.
- W2981034715 hasPrimaryLocation W29810347151 @default.
- W2981034715 hasRelatedWork W1999534544 @default.
- W2981034715 hasRelatedWork W2063106771 @default.
- W2981034715 hasRelatedWork W2286518439 @default.
- W2981034715 hasRelatedWork W2890870264 @default.
- W2981034715 hasRelatedWork W2896397683 @default.
- W2981034715 hasRelatedWork W2906630235 @default.
- W2981034715 hasRelatedWork W2908516238 @default.
- W2981034715 hasRelatedWork W2931830277 @default.
- W2981034715 hasRelatedWork W2981034715 @default.
- W2981034715 hasRelatedWork W3186072842 @default.
- W2981034715 hasVolume "15" @default.
- W2981034715 isParatext "false" @default.
- W2981034715 isRetracted "false" @default.
- W2981034715 magId "2981034715" @default.
- W2981034715 workType "article" @default.