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• W2981148120 abstract "Introduction Subaortic stenosis(SAS) accounts for 8–30% of patients with congenital left ventricular outflow tract obstructions. Allthough progressive SAS occurs in many patients, the exact etiology and factors contributing to progression remains unknown. In this study, we evaluated the natural course of SAS, associated aortic regurgitation (AR), the factors affecting the progression of SAS and AR and the outcomes of surgery during the long-term follow-up with echocardiography. Materials and Methods The study included 105 patients who were evaluated and followed with echocardiography at our institution between 1990 and 2017 with SAS, consisting of either a thin ridge or a thicker but discrete obstruction with a muscular base. Patients with incomplete medical records, abnormal ventricular function, and lesions other than AR were excluded. The last examination prior to any surgical intervention provided our final measurements. The level of narrowing of the LVOT, the distance between right coronary cusp and ridge and the anulus of the aortic valve were determined with two-dimensional echocardiography. Continuous-wave Doppler was used through an apical five-chamber view to record the maximum peak and mean systolic instantaneous gradient across the supravalvular narrowing. A multivariate analysis with Cox proportional hazards modeling was performed to adjust for the different distributions of variables between groups. The enter method was used in logistic regression analysis. Results Among 105 patients (median, 5 years at initial echocardiography), 64% were male and 36% were female. The patients were followed median 6.6 years. Aortic valve morphology was tricuspit in 95.2% and bicuspid in 4.8%. The median distance of discret membran from the right coronary cusp was 6.4 mm. The degree of SAS staid the same in 60%, progressed in 29% and 11% underwent surgery after initial echocardiography. AR did not develope in 21(20%), not deteriorate in 41(39%) and progressed in 43(41%) patients. Surgery was performed in 38(63.8%) patients. 6(5.7%) patients underwent reoperation. Conclussion We recommend careful and frequent evaluation for patients with moderate stenosis because surgery may be needed depending on the severity of stenosis and AR. Postoperatively, follow-up is required." @default.
• W2981148120 created "2019-10-25" @default.
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• W2981148120 date "2019-06-01" @default.
• W2981148120 modified "2023-10-02" @default.
• W2981148120 title "GP32 Echocardiographic follow-up of children with subaortic stenosis" @default.
• W2981148120 doi "https://doi.org/10.1136/archdischild-2019-epa.98" @default.
• W2981148120 hasPublicationYear "2019" @default.
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