Matches in SemOpenAlex for { <https://semopenalex.org/work/W2981152942> ?p ?o ?g. }
- W2981152942 endingPage "438" @default.
- W2981152942 startingPage "393" @default.
- W2981152942 abstract "Non-targeted nanoparticles are capable of entering cells, passing through different subcellular compartments and accumulating on their surface a protein corona that changes over time. In this study, we used metal oxide nanoparticles with iron-oxide core covered with titanium dioxide shell (Fe3O4@TiO2), with a single layer of covalently bound dopamine covering the nanoparticle surface. Mixing nanoparticles with cellular protein isolates showed that these nanoparticles can form complexes with numerous cellular proteins. The addition of non-toxic quantities of nano-particles to HeLa cell culture resulted in their non-specific uptake and accumulation of protein corona on nanoparticle surface. TfRC, Hsp90 and PARP were followed as representative protein components of nanoparticle corona; each protein bound to nanoparticles with different affinity. The presence of nanoparticles in cells also mildly modulated gene expression on the level of mRNA. In conclusion, cells exposed to non-targeted nanoparticles show subtle but numerous changes that are consistent from one experiment to another." @default.
- W2981152942 created "2019-10-25" @default.
- W2981152942 creator A5000779488 @default.
- W2981152942 creator A5000972648 @default.
- W2981152942 creator A5010338995 @default.
- W2981152942 creator A5010795041 @default.
- W2981152942 creator A5013199232 @default.
- W2981152942 creator A5014162383 @default.
- W2981152942 creator A5014917637 @default.
- W2981152942 creator A5017977288 @default.
- W2981152942 creator A5024456614 @default.
- W2981152942 creator A5025803088 @default.
- W2981152942 creator A5032052556 @default.
- W2981152942 creator A5039034888 @default.
- W2981152942 creator A5069788517 @default.
- W2981152942 creator A5078804534 @default.
- W2981152942 date "2019-10-02" @default.
- W2981152942 modified "2023-10-14" @default.
- W2981152942 title "Protein Binding Effects of Dopamine Coated Titanium Dioxide Shell Nanoparticles" @default.
- W2981152942 cites W1261761915 @default.
- W2981152942 cites W1958044292 @default.
- W2981152942 cites W1968500407 @default.
- W2981152942 cites W1999315675 @default.
- W2981152942 cites W2002741280 @default.
- W2981152942 cites W2011696876 @default.
- W2981152942 cites W2031036131 @default.
- W2981152942 cites W2036930872 @default.
- W2981152942 cites W2053619773 @default.
- W2981152942 cites W2055012138 @default.
- W2981152942 cites W2076425489 @default.
- W2981152942 cites W2076542944 @default.
- W2981152942 cites W2077561265 @default.
- W2981152942 cites W2091530533 @default.
- W2981152942 cites W2092702366 @default.
- W2981152942 cites W2093743824 @default.
- W2981152942 cites W2103666075 @default.
- W2981152942 cites W2107665951 @default.
- W2981152942 cites W2110634891 @default.
- W2981152942 cites W2131400318 @default.
- W2981152942 cites W2133465414 @default.
- W2981152942 cites W2133825629 @default.
- W2981152942 cites W2141920788 @default.
- W2981152942 cites W2142521148 @default.
- W2981152942 cites W2145865499 @default.
- W2981152942 cites W2146512944 @default.
- W2981152942 cites W2151213561 @default.
- W2981152942 cites W2158217645 @default.
- W2981152942 cites W2164708087 @default.
- W2981152942 cites W2167933028 @default.
- W2981152942 cites W2168117954 @default.
- W2981152942 cites W2302311597 @default.
- W2981152942 cites W2312972125 @default.
- W2981152942 cites W2507588877 @default.
- W2981152942 cites W2508275214 @default.
- W2981152942 cites W4242175742 @default.
- W2981152942 cites W4255902718 @default.
- W2981152942 cites W659335540 @default.
- W2981152942 doi "https://doi.org/10.33218/prnano2(4).190802.1" @default.
- W2981152942 hasPublicationYear "2019" @default.
- W2981152942 type Work @default.
- W2981152942 sameAs 2981152942 @default.
- W2981152942 citedByCount "4" @default.
- W2981152942 countsByYear W29811529422021 @default.
- W2981152942 countsByYear W29811529422022 @default.
- W2981152942 crossrefType "journal-article" @default.
- W2981152942 hasAuthorship W2981152942A5000779488 @default.
- W2981152942 hasAuthorship W2981152942A5000972648 @default.
- W2981152942 hasAuthorship W2981152942A5010338995 @default.
- W2981152942 hasAuthorship W2981152942A5010795041 @default.
- W2981152942 hasAuthorship W2981152942A5013199232 @default.
- W2981152942 hasAuthorship W2981152942A5014162383 @default.
- W2981152942 hasAuthorship W2981152942A5014917637 @default.
- W2981152942 hasAuthorship W2981152942A5017977288 @default.
- W2981152942 hasAuthorship W2981152942A5024456614 @default.
- W2981152942 hasAuthorship W2981152942A5025803088 @default.
- W2981152942 hasAuthorship W2981152942A5032052556 @default.
- W2981152942 hasAuthorship W2981152942A5039034888 @default.
- W2981152942 hasAuthorship W2981152942A5069788517 @default.
- W2981152942 hasAuthorship W2981152942A5078804534 @default.
- W2981152942 hasBestOaLocation W29811529421 @default.
- W2981152942 hasConcept C12554922 @default.
- W2981152942 hasConcept C1491633281 @default.
- W2981152942 hasConcept C155672457 @default.
- W2981152942 hasConcept C171250308 @default.
- W2981152942 hasConcept C185592680 @default.
- W2981152942 hasConcept C191897082 @default.
- W2981152942 hasConcept C192562407 @default.
- W2981152942 hasConcept C2777366897 @default.
- W2981152942 hasConcept C2777593239 @default.
- W2981152942 hasConcept C2778889443 @default.
- W2981152942 hasConcept C2779089622 @default.
- W2981152942 hasConcept C55493867 @default.
- W2981152942 hasConcept C86803240 @default.
- W2981152942 hasConceptScore W2981152942C12554922 @default.
- W2981152942 hasConceptScore W2981152942C1491633281 @default.
- W2981152942 hasConceptScore W2981152942C155672457 @default.
- W2981152942 hasConceptScore W2981152942C171250308 @default.
- W2981152942 hasConceptScore W2981152942C185592680 @default.