Matches in SemOpenAlex for { <https://semopenalex.org/work/W2981392756> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2981392756 endingPage "105949" @default.
- W2981392756 startingPage "105949" @default.
- W2981392756 abstract "Abstract The solubility profile of apixaban in pure and mixed solvents within the temperature range from (288.15 to 328.15) K under atmosphere pressure (101.3 kPa) was studied and evaluated by some thermodynamics models. The solid state of apixaban in equilibrated form was characterized using powder X-ray diffraction (PXRD) technique. The maximum mole solubility in pure solvents was obtained in 1, 4-dioxane (3.648 × 10−3) at 328.15 K, and followed by methanol (1.967 × 10−3), acetone (7.885 × 10−4),ethanol (6.049 × 10−4), isopropanol (3.806 × 10−4), ethyl acetate (2.266 × 10−4), n-hexane (1.883 × 10−4), water (3.989 × 10−5). The solubility was quite small. Therefore, the solubility profile of apixaban in mixtures of (1, 4-dioxane + water) was further studied. Moreover, it increased at first and then decreased with the increasing mass fraction of 1, 4-dioxane. Moreover, the extended Hildebrand solubility approach (EHSA) was applied to evaluate the co-solvency phenomenon in mixed solvent at 298.15 K. In the following, the analysis of apparent thermodynamic properties indicates that the dissolution process in all selected solvents is an endothermic and entropy driven process." @default.
- W2981392756 created "2019-11-01" @default.
- W2981392756 creator A5018985219 @default.
- W2981392756 creator A5033256088 @default.
- W2981392756 creator A5033542985 @default.
- W2981392756 creator A5042973046 @default.
- W2981392756 creator A5043542087 @default.
- W2981392756 creator A5061118924 @default.
- W2981392756 creator A5089479936 @default.
- W2981392756 date "2020-05-01" @default.
- W2981392756 modified "2023-09-24" @default.
- W2981392756 title "Dissolution behavior and thermodynamic properties of apixaban in pure and mixed solvents" @default.
- W2981392756 cites W1507763452 @default.
- W2981392756 cites W1564690174 @default.
- W2981392756 cites W1600161348 @default.
- W2981392756 cites W1975634579 @default.
- W2981392756 cites W1981788205 @default.
- W2981392756 cites W2013918877 @default.
- W2981392756 cites W2060482516 @default.
- W2981392756 cites W2072476365 @default.
- W2981392756 cites W2079854206 @default.
- W2981392756 cites W2118857793 @default.
- W2981392756 cites W2149388786 @default.
- W2981392756 cites W2150559203 @default.
- W2981392756 cites W2162508946 @default.
- W2981392756 cites W2219610164 @default.
- W2981392756 cites W2279847866 @default.
- W2981392756 cites W2320374844 @default.
- W2981392756 cites W2324737379 @default.
- W2981392756 cites W2334138621 @default.
- W2981392756 cites W2538338339 @default.
- W2981392756 cites W2546545069 @default.
- W2981392756 cites W2741126211 @default.
- W2981392756 cites W2794657954 @default.
- W2981392756 cites W2951050136 @default.
- W2981392756 doi "https://doi.org/10.1016/j.jct.2019.105949" @default.
- W2981392756 hasPublicationYear "2020" @default.
- W2981392756 type Work @default.
- W2981392756 sameAs 2981392756 @default.
- W2981392756 citedByCount "2" @default.
- W2981392756 countsByYear W29813927562020 @default.
- W2981392756 countsByYear W29813927562021 @default.
- W2981392756 crossrefType "journal-article" @default.
- W2981392756 hasAuthorship W2981392756A5018985219 @default.
- W2981392756 hasAuthorship W2981392756A5033256088 @default.
- W2981392756 hasAuthorship W2981392756A5033542985 @default.
- W2981392756 hasAuthorship W2981392756A5042973046 @default.
- W2981392756 hasAuthorship W2981392756A5043542087 @default.
- W2981392756 hasAuthorship W2981392756A5061118924 @default.
- W2981392756 hasAuthorship W2981392756A5089479936 @default.
- W2981392756 hasConcept C121332964 @default.
- W2981392756 hasConcept C164705383 @default.
- W2981392756 hasConcept C178790620 @default.
- W2981392756 hasConcept C185592680 @default.
- W2981392756 hasConcept C2776301958 @default.
- W2981392756 hasConcept C2778661090 @default.
- W2981392756 hasConcept C2779161974 @default.
- W2981392756 hasConcept C2780638905 @default.
- W2981392756 hasConcept C71924100 @default.
- W2981392756 hasConcept C88380143 @default.
- W2981392756 hasConcept C97355855 @default.
- W2981392756 hasConceptScore W2981392756C121332964 @default.
- W2981392756 hasConceptScore W2981392756C164705383 @default.
- W2981392756 hasConceptScore W2981392756C178790620 @default.
- W2981392756 hasConceptScore W2981392756C185592680 @default.
- W2981392756 hasConceptScore W2981392756C2776301958 @default.
- W2981392756 hasConceptScore W2981392756C2778661090 @default.
- W2981392756 hasConceptScore W2981392756C2779161974 @default.
- W2981392756 hasConceptScore W2981392756C2780638905 @default.
- W2981392756 hasConceptScore W2981392756C71924100 @default.
- W2981392756 hasConceptScore W2981392756C88380143 @default.
- W2981392756 hasConceptScore W2981392756C97355855 @default.
- W2981392756 hasLocation W29813927561 @default.
- W2981392756 hasOpenAccess W2981392756 @default.
- W2981392756 hasPrimaryLocation W29813927561 @default.
- W2981392756 hasRelatedWork W1983110884 @default.
- W2981392756 hasRelatedWork W1986438144 @default.
- W2981392756 hasRelatedWork W2020471473 @default.
- W2981392756 hasRelatedWork W2051936898 @default.
- W2981392756 hasRelatedWork W2073515118 @default.
- W2981392756 hasRelatedWork W2083651180 @default.
- W2981392756 hasRelatedWork W2800321151 @default.
- W2981392756 hasRelatedWork W2950490047 @default.
- W2981392756 hasRelatedWork W3200420976 @default.
- W2981392756 hasRelatedWork W2507184690 @default.
- W2981392756 hasVolume "144" @default.
- W2981392756 isParatext "false" @default.
- W2981392756 isRetracted "false" @default.
- W2981392756 magId "2981392756" @default.
- W2981392756 workType "article" @default.