Matches in SemOpenAlex for { <https://semopenalex.org/work/W2981495822> ?p ?o ?g. }
- W2981495822 abstract "Abstract Around 30% of individuals with schizophrenia remain symptomatic and markedly impaired despite standard antipsychotic treatment and are considered to be treatment-resistant. The only licensed medication for treatment-resistant schizophrenia (TRS) is the antipsychotic clozapine, which has been shown to improve symptoms and functioning in the majority of patients. Early identification of TRS patients is an important goal for personalized psychiatry, with the aim to facilitate timely access to effective treatment. Previous studies have strongly implicated several clinical features as predictive of TRS, such as a younger age at onset of psychosis and poor premorbid functioning. However, to date, robust biomarker or genetic studies have been scarce. This chapter provides a summary of our current understanding of the genetic etiology of TRS, discusses the key challenges facing this area of research, and assesses the potential for treatment response prediction in the future." @default.
- W2981495822 created "2019-11-01" @default.
- W2981495822 creator A5013467589 @default.
- W2981495822 creator A5032995667 @default.
- W2981495822 creator A5047654824 @default.
- W2981495822 date "2020-01-01" @default.
- W2981495822 modified "2023-10-16" @default.
- W2981495822 title "Genomic treatment response prediction in schizophrenia" @default.
- W2981495822 cites W1565231669 @default.
- W2981495822 cites W1982177100 @default.
- W2981495822 cites W1982377534 @default.
- W2981495822 cites W1986206460 @default.
- W2981495822 cites W1987942611 @default.
- W2981495822 cites W2000583638 @default.
- W2981495822 cites W2010425739 @default.
- W2981495822 cites W2013514700 @default.
- W2981495822 cites W2019695618 @default.
- W2981495822 cites W2020663825 @default.
- W2981495822 cites W2021053325 @default.
- W2981495822 cites W2029856455 @default.
- W2981495822 cites W2030940173 @default.
- W2981495822 cites W2036480935 @default.
- W2981495822 cites W2037820216 @default.
- W2981495822 cites W2043580488 @default.
- W2981495822 cites W2050547635 @default.
- W2981495822 cites W2056692846 @default.
- W2981495822 cites W2059944156 @default.
- W2981495822 cites W2067507716 @default.
- W2981495822 cites W2067571971 @default.
- W2981495822 cites W2068898125 @default.
- W2981495822 cites W2068995113 @default.
- W2981495822 cites W2069011875 @default.
- W2981495822 cites W2078881206 @default.
- W2981495822 cites W2086619421 @default.
- W2981495822 cites W2086869274 @default.
- W2981495822 cites W2087792353 @default.
- W2981495822 cites W2094683019 @default.
- W2981495822 cites W2101357408 @default.
- W2981495822 cites W2102659586 @default.
- W2981495822 cites W2105527159 @default.
- W2981495822 cites W2108968692 @default.
- W2981495822 cites W2111564097 @default.
- W2981495822 cites W2116514399 @default.
- W2981495822 cites W2138231636 @default.
- W2981495822 cites W2161527093 @default.
- W2981495822 cites W2163924952 @default.
- W2981495822 cites W2170090311 @default.
- W2981495822 cites W2253685540 @default.
- W2981495822 cites W2270499844 @default.
- W2981495822 cites W2278070452 @default.
- W2981495822 cites W2280484203 @default.
- W2981495822 cites W2284234055 @default.
- W2981495822 cites W2290746927 @default.
- W2981495822 cites W2328257377 @default.
- W2981495822 cites W2517254183 @default.
- W2981495822 cites W2560754155 @default.
- W2981495822 cites W2578041951 @default.
- W2981495822 cites W2586701058 @default.
- W2981495822 cites W2605379571 @default.
- W2981495822 cites W2608097734 @default.
- W2981495822 cites W2623053349 @default.
- W2981495822 cites W2725988230 @default.
- W2981495822 cites W2751073462 @default.
- W2981495822 cites W2759241620 @default.
- W2981495822 cites W2769997711 @default.
- W2981495822 cites W2777388159 @default.
- W2981495822 cites W2783960693 @default.
- W2981495822 cites W2791643768 @default.
- W2981495822 cites W2794573350 @default.
- W2981495822 cites W2901266236 @default.
- W2981495822 cites W2901387277 @default.
- W2981495822 cites W2912565583 @default.
- W2981495822 cites W2945575042 @default.
- W2981495822 cites W2952673268 @default.
- W2981495822 cites W4211145950 @default.
- W2981495822 cites W4245242700 @default.
- W2981495822 cites W748532525 @default.
- W2981495822 doi "https://doi.org/10.1016/b978-0-12-813176-3.00034-1" @default.
- W2981495822 hasPublicationYear "2020" @default.
- W2981495822 type Work @default.
- W2981495822 sameAs 2981495822 @default.
- W2981495822 citedByCount "1" @default.
- W2981495822 countsByYear W29814958222022 @default.
- W2981495822 crossrefType "book-chapter" @default.
- W2981495822 hasAuthorship W2981495822A5013467589 @default.
- W2981495822 hasAuthorship W2981495822A5032995667 @default.
- W2981495822 hasAuthorship W2981495822A5047654824 @default.
- W2981495822 hasConcept C118552586 @default.
- W2981495822 hasConcept C137627325 @default.
- W2981495822 hasConcept C15744967 @default.
- W2981495822 hasConcept C2776412080 @default.
- W2981495822 hasConcept C2779727114 @default.
- W2981495822 hasConcept C2780494398 @default.
- W2981495822 hasConcept C2780864610 @default.
- W2981495822 hasConcept C2781197716 @default.
- W2981495822 hasConcept C54355233 @default.
- W2981495822 hasConcept C70410870 @default.
- W2981495822 hasConcept C71924100 @default.
- W2981495822 hasConcept C86803240 @default.
- W2981495822 hasConceptScore W2981495822C118552586 @default.