FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2981549197> ?p ?o ?g. }

• W2981549197 endingPage "S1064" @default.
• W2981549197 startingPage "S1063" @default.
• W2981549197 abstract "Thymic carcinoma is a rare tumor that represents a clinical challenge, especially in resource limited settings. The objective of the present study was to characterize patients who presented this disease in Latin-America. From 2014 until 2018, a multinational Latin-American cooperative retrospective cohort study was performed. Patients with histologically confirmed thymic carcinoma were included. Clinical, pathological and treatment variables were collected across 7 participating nations. A total of 31 patients were included. Median age at diagnosis was 58 years old (34-69), 48% (n=15) of individuals were women with all but 2 patients (6.5%) achieving an ECOG performance score <2. All patients debuted with Stage IV disease; 24 patients (66%, [95%CI 62-92%]) as stage IVa and 7 as stage IVb (33%, [95%CI 7-37%]) with a median LDH level of 396.5 U/L (153-1529 U/L) and a median of 2 metastatic sites. 13 (41.9%, [95%CI 25-59%]) patients received preoperatory treatment consisting of chemotherapy (n=8, 42%) and chemoradiotherapy (n=5, 16%). Among these patients only 4 (12.9%) were subjected to surgery, two of which underwent a tumorectomy and 2 a thymectomy. 28 (90%, [95%CI 79.9-100%]) received palliative chemotherapy either with sunitinib (n=7, 25%) or cytotoxic agents. Median overall survival (OS) was reached at 20.2 months (95%CI 19-NA months). Patients who received preoperative treatment had a significantly prolonged OS (17.6 vs 26 months, HR 2.93 [95%CI 1.04-8.27 months], p = 0.03). Thymic carcinoma constitutes an aggressive disease that is often diagnosed in advanced stages. These results suggest that multimodal treatment can be beneficial even in locally advanced cases. Larger clinical trial validating these conclusions are warranted." @default.
• W2981549197 created "2019-11-01" @default.
• W2981549197 creator A5000631349 @default.
• W2981549197 creator A5002304475 @default.
• W2981549197 creator A5004814001 @default.
• W2981549197 creator A5005241227 @default.
• W2981549197 creator A5007170973 @default.
• W2981549197 creator A5008152833 @default.
• W2981549197 creator A5014453416 @default.
• W2981549197 creator A5017633069 @default.
• W2981549197 creator A5017769557 @default.
• W2981549197 creator A5028351604 @default.
• W2981549197 creator A5034618792 @default.
• W2981549197 creator A5035063101 @default.
• W2981549197 creator A5038974897 @default.
• W2981549197 creator A5039125650 @default.
• W2981549197 creator A5039140100 @default.
• W2981549197 creator A5044887899 @default.
• W2981549197 creator A5046116374 @default.
• W2981549197 creator A5052371243 @default.
• W2981549197 creator A5054952510 @default.
• W2981549197 creator A5058117531 @default.
• W2981549197 creator A5059364345 @default.
• W2981549197 creator A5063353819 @default.
• W2981549197 creator A5070081985 @default.
• W2981549197 creator A5074835287 @default.
• W2981549197 creator A5078080026 @default.
• W2981549197 creator A5081511710 @default.
• W2981549197 creator A5087560136 @default.
• W2981549197 creator A5087884322 @default.
• W2981549197 date "2019-10-01" @default.
• W2981549197 modified "2023-10-17" @default.
• W2981549197 title "EP1.15-29 Real World Characterization and Treatment of Patients with Thymic Carcinoma: Lessons from a Latin-American Study (CLICaP-LATimus)" @default.
• W2981549197 doi "https://doi.org/10.1016/j.jtho.2019.08.2364" @default.
• W2981549197 hasPublicationYear "2019" @default.
• W2981549197 type Work @default.
• W2981549197 sameAs 2981549197 @default.
• W2981549197 citedByCount "0" @default.
• W2981549197 crossrefType "journal-article" @default.
• W2981549197 hasAuthorship W2981549197A5000631349 @default.
• W2981549197 hasAuthorship W2981549197A5002304475 @default.
• W2981549197 hasAuthorship W2981549197A5004814001 @default.
• W2981549197 hasAuthorship W2981549197A5005241227 @default.
• W2981549197 hasAuthorship W2981549197A5007170973 @default.
• W2981549197 hasAuthorship W2981549197A5008152833 @default.
• W2981549197 hasAuthorship W2981549197A5014453416 @default.
• W2981549197 hasAuthorship W2981549197A5017633069 @default.
• W2981549197 hasAuthorship W2981549197A5017769557 @default.
• W2981549197 hasAuthorship W2981549197A5028351604 @default.
• W2981549197 hasAuthorship W2981549197A5034618792 @default.
• W2981549197 hasAuthorship W2981549197A5035063101 @default.
• W2981549197 hasAuthorship W2981549197A5038974897 @default.
• W2981549197 hasAuthorship W2981549197A5039125650 @default.
• W2981549197 hasAuthorship W2981549197A5039140100 @default.
• W2981549197 hasAuthorship W2981549197A5044887899 @default.
• W2981549197 hasAuthorship W2981549197A5046116374 @default.
• W2981549197 hasAuthorship W2981549197A5052371243 @default.
• W2981549197 hasAuthorship W2981549197A5054952510 @default.
• W2981549197 hasAuthorship W2981549197A5058117531 @default.
• W2981549197 hasAuthorship W2981549197A5059364345 @default.
• W2981549197 hasAuthorship W2981549197A5063353819 @default.
• W2981549197 hasAuthorship W2981549197A5070081985 @default.
• W2981549197 hasAuthorship W2981549197A5074835287 @default.
• W2981549197 hasAuthorship W2981549197A5078080026 @default.
• W2981549197 hasAuthorship W2981549197A5081511710 @default.
• W2981549197 hasAuthorship W2981549197A5087560136 @default.
• W2981549197 hasAuthorship W2981549197A5087884322 @default.
• W2981549197 hasBestOaLocation W29815491971 @default.
• W2981549197 hasConcept C121608353 @default.
• W2981549197 hasConcept C126322002 @default.
• W2981549197 hasConcept C141071460 @default.
• W2981549197 hasConcept C146357865 @default.
• W2981549197 hasConcept C151730666 @default.
• W2981549197 hasConcept C167135981 @default.
• W2981549197 hasConcept C2776349617 @default.
• W2981549197 hasConcept C2776694085 @default.
• W2981549197 hasConcept C2777910003 @default.
• W2981549197 hasConcept C2779490328 @default.
• W2981549197 hasConcept C71924100 @default.
• W2981549197 hasConcept C72563966 @default.
• W2981549197 hasConcept C86803240 @default.
• W2981549197 hasConcept C90924648 @default.
• W2981549197 hasConceptScore W2981549197C121608353 @default.
• W2981549197 hasConceptScore W2981549197C126322002 @default.
• W2981549197 hasConceptScore W2981549197C141071460 @default.
• W2981549197 hasConceptScore W2981549197C146357865 @default.
• W2981549197 hasConceptScore W2981549197C151730666 @default.
• W2981549197 hasConceptScore W2981549197C167135981 @default.
• W2981549197 hasConceptScore W2981549197C2776349617 @default.
• W2981549197 hasConceptScore W2981549197C2776694085 @default.
• W2981549197 hasConceptScore W2981549197C2777910003 @default.
• W2981549197 hasConceptScore W2981549197C2779490328 @default.
• W2981549197 hasConceptScore W2981549197C71924100 @default.
• W2981549197 hasConceptScore W2981549197C72563966 @default.
• W2981549197 hasConceptScore W2981549197C86803240 @default.
• W2981549197 hasConceptScore W2981549197C90924648 @default.
• W2981549197 hasIssue "10" @default.
• W2981549197 hasLocation W29815491971 @default.

• next