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• W2981566506 abstract "Plant cultivation on spacecraft or planetary outposts is a promising and actual perspective both for food and bioactive molecules production. To this aim, plants response to ionizing radiations, as an important component of space radiation, must be assessed through on-ground experiments due to the potentially fatal effects on living systems. Hereby, we investigated the effects of X-rays and -rays exposure on tomato ‘hairy root’ cultures (HRCs), which represent a solid platform for the production of pharmaceutically relevant molecules, including metabolites and recombinant proteins. In a space application perspective, we used a HRC system previously fortified through the accumulation of anthocyanins, which are known for their anti-oxidant properties. Roots were independently exposed to different photon radiations, namely X-rays (250 kV) and -rays (Co60, 1.25 MeV), both at the absorbed dose levels of 0.5, 5 and 10 Gy. Molecular changes induced in the proteome of HRCs were investigated by a comparative approach based on Two-Dimensional Difference In-Gel electrophoresis (2D-DIGE) technology, which allowed to highlight dynamic processes activated by these environmental stresses. Results revealed a comparable response to both photon treatments. In particular, the presence of differentially represented proteins were observed only when roots were exposed to 5 or 10 Gy of X-rays or -rays, while no variations were appreciated at 0.5 Gy of both radiations, when compared with unexposed control. Differentially represented proteins were identified by mass spectrometry procedures and their functional interactions were analyzed, revealing variations in the activation of stress response integrated mechanisms as well as in carbon/energy and protein metabolism. Specific results from above-mentioned procedures were validated by immunoblotting. Finally, a morphometric analysis verified the absence of significant alterations in the development of HRCs, allowing to ascribe the observed variations of protein expression to processes of acclimation to ionizing radiations. Overall results contribute to a meaningful risk evaluation for biological systems exposed to extra-terrestrial environments, in the perspective of manned interplanetary missions planned for the near future." @default.
• W2981566506 created "2019-11-01" @default.
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• W2981566506 date "2019-10-24" @default.
• W2981566506 modified "2023-10-16" @default.
• W2981566506 title "Effects of Simulated Space Radiations on the Tomato Root Proteome" @default.
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• W2981566506 cites W1605206360 @default.
• W2981566506 cites W1964638001 @default.
• W2981566506 cites W1965398768 @default.
• W2981566506 cites W1973352575 @default.
• W2981566506 cites W1980223943 @default.
• W2981566506 cites W1983527131 @default.
• W2981566506 cites W1985786559 @default.
• W2981566506 cites W1988608958 @default.
• W2981566506 cites W2004340430 @default.
• W2981566506 cites W2019400077 @default.
• W2981566506 cites W2022524895 @default.
• W2981566506 cites W2022961230 @default.
• W2981566506 cites W2025696130 @default.
• W2981566506 cites W2030433684 @default.
• W2981566506 cites W2035298085 @default.
• W2981566506 cites W2035412505 @default.
• W2981566506 cites W2036440960 @default.
• W2981566506 cites W2041493424 @default.
• W2981566506 cites W2041868728 @default.
• W2981566506 cites W2051761091 @default.
• W2981566506 cites W2055542427 @default.
• W2981566506 cites W2059324411 @default.
• W2981566506 cites W2059674956 @default.
• W2981566506 cites W2060991867 @default.
• W2981566506 cites W2063824133 @default.
• W2981566506 cites W2070756073 @default.
• W2981566506 cites W2072008344 @default.
• W2981566506 cites W2072654764 @default.
• W2981566506 cites W2072919482 @default.
• W2981566506 cites W2082084462 @default.
• W2981566506 cites W2082706134 @default.
• W2981566506 cites W2084502505 @default.
• W2981566506 cites W2092401751 @default.
• W2981566506 cites W2096173332 @default.
• W2981566506 cites W2097961562 @default.
• W2981566506 cites W2098170274 @default.
• W2981566506 cites W2103647822 @default.
• W2981566506 cites W2112220141 @default.
• W2981566506 cites W2112935528 @default.
• W2981566506 cites W2113803226 @default.
• W2981566506 cites W2115777587 @default.
• W2981566506 cites W2119777125 @default.
• W2981566506 cites W2120213697 @default.
• W2981566506 cites W2126386203 @default.
• W2981566506 cites W2128773208 @default.
• W2981566506 cites W2129553777 @default.
• W2981566506 cites W2131064775 @default.
• W2981566506 cites W2135581618 @default.
• W2981566506 cites W2136527769 @default.
• W2981566506 cites W2136719061 @default.
• W2981566506 cites W2140189582 @default.
• W2981566506 cites W2166589324 @default.
• W2981566506 cites W2258655586 @default.
• W2981566506 cites W2326176611 @default.
• W2981566506 cites W2427841886 @default.
• W2981566506 cites W2526872567 @default.
• W2981566506 cites W2563844086 @default.
• W2981566506 cites W2604349127 @default.
• W2981566506 cites W2606160044 @default.
• W2981566506 cites W2683936324 @default.
• W2981566506 cites W2758320815 @default.
• W2981566506 cites W2759872834 @default.
• W2981566506 cites W2774539825 @default.
• W2981566506 cites W2777463186 @default.
• W2981566506 cites W2783080184 @default.
• W2981566506 cites W2792108715 @default.
• W2981566506 cites W2793575511 @default.
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• W2981566506 cites W2808296027 @default.
• W2981566506 cites W2847812345 @default.
• W2981566506 cites W2905827805 @default.
• W2981566506 cites W2909186883 @default.
• W2981566506 cites W2912582958 @default.
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• W2981566506 doi "https://doi.org/10.3389/fpls.2019.01334" @default.
• W2981566506 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6821793" @default.
• W2981566506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31708949" @default.
• W2981566506 hasPublicationYear "2019" @default.
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