Matches in SemOpenAlex for { <https://semopenalex.org/work/W2981567796> ?p ?o ?g. }
- W2981567796 endingPage "107" @default.
- W2981567796 startingPage "107" @default.
- W2981567796 abstract "The burden of cardiovascular disease (CVD) remains high globally and in the United States despite the availability of pharmaceuticals aimed at its prevention and treatment. An invention by Summit Innovation Labs, which is a formula consisting of a unique blend of select polyphenols (i.e., curcumin, quercetin, resveratrol), vitamin K2 as menaquinone-7, and magnesium, was recently developed to modulate the impact of the specific drivers of CVD, namely, vascular calcification, oxidative stress, and chronic inflammation. The SIL formulation is a dietary supplement that was designed leveraging the more bioavailable forms of ingredients with poor absorption, such as curcumin and quercetin. Each ingredient within the SIL formulation has been shown to contribute to CVD risk reduction by moderating the effect of CVD triggers, thereby providing a holistic prevention strategy for CVD in the healthy population. This review focuses on recently published clinical data to support the safety profile of these ingredients following oral administration. The preponderance of clinical trial data reviewed support the overall safety of the bioactives when used singly or in combination. The most commonly reported adverse effects were generally mild dose-related gastrointestinal disturbances, which may be alleviated with diet in some cases. In light of these, we conclude that the combination of the ingredients in the SIL formulation is reasonably expected to be safe." @default.
- W2981567796 created "2019-11-01" @default.
- W2981567796 creator A5029987891 @default.
- W2981567796 creator A5047821174 @default.
- W2981567796 creator A5077960028 @default.
- W2981567796 date "2019-10-22" @default.
- W2981567796 modified "2023-09-26" @default.
- W2981567796 title "A Unique Formulation of Cardioprotective Bio-Actives: An Overview of Their Safety Profile" @default.
- W2981567796 cites W1511966243 @default.
- W2981567796 cites W1559010782 @default.
- W2981567796 cites W1560004065 @default.
- W2981567796 cites W1604068141 @default.
- W2981567796 cites W1606516178 @default.
- W2981567796 cites W1823340438 @default.
- W2981567796 cites W1833436358 @default.
- W2981567796 cites W1835574744 @default.
- W2981567796 cites W1846632583 @default.
- W2981567796 cites W1847692633 @default.
- W2981567796 cites W1879989348 @default.
- W2981567796 cites W1886477676 @default.
- W2981567796 cites W1896811967 @default.
- W2981567796 cites W1914622032 @default.
- W2981567796 cites W1928906432 @default.
- W2981567796 cites W1966127027 @default.
- W2981567796 cites W1968985960 @default.
- W2981567796 cites W1970882491 @default.
- W2981567796 cites W1975258993 @default.
- W2981567796 cites W1975287120 @default.
- W2981567796 cites W1975828757 @default.
- W2981567796 cites W1976942216 @default.
- W2981567796 cites W1977017932 @default.
- W2981567796 cites W1977553069 @default.
- W2981567796 cites W1978184244 @default.
- W2981567796 cites W1979886311 @default.
- W2981567796 cites W1980327119 @default.
- W2981567796 cites W1980567930 @default.
- W2981567796 cites W1980855715 @default.
- W2981567796 cites W1995132728 @default.
- W2981567796 cites W1996866382 @default.
- W2981567796 cites W1998616007 @default.
- W2981567796 cites W2000248590 @default.
- W2981567796 cites W2001739374 @default.
- W2981567796 cites W2001994991 @default.
- W2981567796 cites W2007492343 @default.
- W2981567796 cites W2011336591 @default.
- W2981567796 cites W2019242764 @default.
- W2981567796 cites W2021202160 @default.
- W2981567796 cites W2026939902 @default.
- W2981567796 cites W2029025809 @default.
- W2981567796 cites W2031213396 @default.
- W2981567796 cites W2031814313 @default.
- W2981567796 cites W2035864756 @default.
- W2981567796 cites W2037863187 @default.
- W2981567796 cites W2040123698 @default.
- W2981567796 cites W2052419452 @default.
- W2981567796 cites W2053510668 @default.
- W2981567796 cites W2054659940 @default.
- W2981567796 cites W2056667035 @default.
- W2981567796 cites W2057933641 @default.
- W2981567796 cites W2058579856 @default.
- W2981567796 cites W2062269191 @default.
- W2981567796 cites W2063483498 @default.
- W2981567796 cites W2064044450 @default.
- W2981567796 cites W2065068389 @default.
- W2981567796 cites W2067670322 @default.
- W2981567796 cites W2069353566 @default.
- W2981567796 cites W2070997298 @default.
- W2981567796 cites W2074601722 @default.
- W2981567796 cites W2077166822 @default.
- W2981567796 cites W2077214005 @default.
- W2981567796 cites W2077431908 @default.
- W2981567796 cites W2079383900 @default.
- W2981567796 cites W2079662265 @default.
- W2981567796 cites W2079725826 @default.
- W2981567796 cites W2081187091 @default.
- W2981567796 cites W2082054121 @default.
- W2981567796 cites W2088355928 @default.
- W2981567796 cites W2092032160 @default.
- W2981567796 cites W2096837196 @default.
- W2981567796 cites W2097950056 @default.
- W2981567796 cites W2099023764 @default.
- W2981567796 cites W2100809193 @default.
- W2981567796 cites W2103841489 @default.
- W2981567796 cites W2104568691 @default.
- W2981567796 cites W2108128042 @default.
- W2981567796 cites W2110111555 @default.
- W2981567796 cites W2110989336 @default.
- W2981567796 cites W2111797455 @default.
- W2981567796 cites W2114721006 @default.
- W2981567796 cites W2114809598 @default.
- W2981567796 cites W2119582385 @default.
- W2981567796 cites W2119696446 @default.
- W2981567796 cites W2120166750 @default.
- W2981567796 cites W2120487488 @default.
- W2981567796 cites W2130546039 @default.
- W2981567796 cites W2130955150 @default.
- W2981567796 cites W2138270719 @default.
- W2981567796 cites W2141116781 @default.