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- W2981868064 abstract "Abstract Background Late infarct size (IS) after STEMI is a determinant of subsequent mortality. Late Gadolinium enhancement in cardiac magnetic resonance imaging (LGE-CMRI) is the gold standard for IS measurement, however, it is not readily accessible in many areas. Aims To evaluate the value of early baseline 2D-echocardiographic global longitudinal strain (GLS) for prediction of late IS after STEMI. Methods From October 2017 to July 2018, we studied 100 patients with their 1st anterior STEMI treated with a PPCI. Baseline GLS calculation was performed within 48 hours of admission. The average value of the 9 segments supplied by the LAD was assessed separately (anterior GLS). Infarct size was assessed 3 months later using LGE-CMRI, and large infarcts were defined as ≥20% LV myocardium covered by scar. Results Based on CMRI, patients were divided into 2 groups; 57 patients with large infarcts (group I) and 43 patients with small infarcts (group II). Both groups were matched in all baseline demographics and risk factors. There was a good and significant correlation between GLS and the degree of myocardium affected by scar (r=−0.840, P<0.001). This correlation was even higher for anterior GLS (r=−0.867, P<0.001). ROC analysis showed a cut-off point of GLS (−13%) that identified large late IS with a sensitivity and specificity of 66.7% and 88.4% respectively (AUC= 0.85). For anterior GLS, the cut-off point was −9.6% (Sensitivity 94%, specificity 86%, AUC= 0.9). Baseline 2D-GLS & Late LGE-CMRI Conclusion Baseline GLS significantly predicts and correlates well with late IS after anterior STEMI." @default.
- W2981868064 created "2019-11-01" @default.
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- W2981868064 date "2019-10-01" @default.
- W2981868064 modified "2023-09-27" @default.
- W2981868064 title "P617Early global longitudinal strain predicts late infarct size in patients with anterior ST-segment elevation myocardial infarction treated with a primary percutaneous coronary intervention" @default.
- W2981868064 doi "https://doi.org/10.1093/eurheartj/ehz747.0226" @default.
- W2981868064 hasPublicationYear "2019" @default.
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