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• W2981894920 endingPage "108644" @default.
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• W2981894920 abstract "Tetranychus cinnabarinus (Boisduval) is a major pest that harms crops and vegetables worldwide. Scopoletin is a promising acaricidal compound. Our previous study demonstrated that the acaricidal mechanism of scopoletin may be via disrupting intracellular Ca2+ homeostasis and calcium signaling pathway. However, the mechanism underlying the specific target location of scopoletin against T. cinnabarinus remains unclear. In this study, the full-length cDNA of the calcium channel (TcT-VDCC) gene from T. cinnabarinus was cloned and characterized. The TcT-VDCC gene is expressed at all developmental stages of T. cinnabarinus but is highly expressed in the larval and nymphal stages. The TcT-VDCC gene was significantly upregulated after treatment with scopoletin, and the RNAi method was used to feed the dsRNA in T. cinnabarinus to silence the TcT-VDCC gene and reduce its sensitivity to scopoletin. The results showed that the acaricidal mechanism of scopoletin on T. cinnabarinus may be related to TcT-VDCC." @default.
• W2981894920 created "2019-11-01" @default.
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• W2981894920 date "2020-01-01" @default.
• W2981894920 modified "2023-09-25" @default.
• W2981894920 title "Silencing T-type voltage-gated calcium channel gene reduces the sensitivity of Tetranychus cinnabarinus (Boisduval) to scopoletin" @default.
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• W2981894920 doi "https://doi.org/10.1016/j.cbpc.2019.108644" @default.
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