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• W2981905844 abstract "S02: Harmonizing insights from intervention studies, contextual information and resource availability to develop policy advocacy for clean cooking and domestic fuel adoption in Africa, Room 417, Floor 4, August 27, 2019, 10:30 AM - 12:00 PM Background/Aim: Exposure to household air pollution from cooking with solid fuel accounts for 3 million premature deaths yearly and has been linked to adverse pregnancy outcomes. In Nigeria, 70% of households cook with kerosene or firewood. A randomized controlled trial was undertaken in Ibadan, Nigeria to determine the impact of cooking with kerosene or firewood on personal exposures, the health of pregnant women and pregnancy outcomes. Methods: Three hundred twenty four pregnant women were randomized to either control (C-continued cooking using own kerosene/firewood stove; or intervention groups (E-received CleanCook stove). Ultrasonography and blood pressure measurements were performed at six visits during pregnancy. 72-hour personal exposure monitoring of particulate matter with diameter less than 2.5 micrometers (PM2.5) was performed in the second and third trimester. Birth outcomes (miscarriages, pre-term deliveries and birth weights) were recorded. Placenta was collected at birth and analyzed for chronic hypoxia and biomarker levels of hypoxia inducing factor. Results: Of the enrolled participants, 18 dropped out of the study (8 E, 10 C). Mean birthweight for the ethanol and control groups was 3076.2 and 2988.0g, respectively; the difference, 88.2g (95% confidence interval: -18.0g to 194.5g), was not statistically significant (p=0.103). However, after adjusting for marital status and BMI, the difference reached statistical significance (p=0.020). Average gestational age at delivery was significantly (p=0.015) higher in ethanol group (39.2 weeks) compared to controls (38.2 weeks). There were fewer preterm infants (<37 weeks), stillbirths, miscarriages, and neonatal deaths in the ethanol group compared to controls. The percentage of miscarriages, stillbirths, or neonatal deaths was twice as high in controls compared to the ethanol group (9.9% vs. 4.6%; p=0.037). The likelihood of developing hypertension at term and diastolic BP was significantly lower in the ethanol group. Conclusions: Replacing kerosene and firewood with ethanol in pregnant Nigerian women improved pregnancy outcomes." @default.
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• W2981905844 date "2019-10-01" @default.
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• W2981905844 title "Can transition to a cleaner fuel from Kerosene or firewood be beneficial in pregnant Nigerian women?" @default.
• W2981905844 doi "https://doi.org/10.1097/01.ee9.0000609180.76915.db" @default.
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