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- W2982148110 abstract "Abstract An efficient and modular entry to α‐halogenated amides and esters is reported. This reaction is based on an underestimated double electrophilic activation of ynamides sequentially involving highly reactive activated keteniminium and iminium ions. Upon simple reaction with HCl and an electrophilic halogenation reagent in the presence of water or an alcohol, a broad range of ynamides can be transformed, in a highly divergent manner, to α‐halo amides and esters with high efficiency and under mild conditions." @default.
- W2982148110 created "2019-11-01" @default.
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- W2982148110 date "2019-11-14" @default.
- W2982148110 modified "2023-10-17" @default.
- W2982148110 title "Efficient and Divergent Synthesis of α‐Halogenated Amides and Esters by Double Electrophilic Activation of Ynamides" @default.
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- W2982148110 doi "https://doi.org/10.1002/anie.201911722" @default.
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