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- W2982201110 abstract "Objective: To reveal the prevalence and the related factors of hepatitis B (HepB) virus infection among HIV/AIDS patients. Methods: We conducted a cross-sectional study in two HIV clinics, affiliated to local Centers of Disease Control and Prevention in Guangxi Zhuang Autonomous Regional. A face-to-face interview, with questionnaire was conducted to collect information on socio-demographic characteristics, drug use, and sexual behavior. Blood samples were used to test HBsAg. χ(2) test or Fisher's exact test and unconditional logistic regression models were used to identify the influencing factors. Results: The prevalence of HBV and HIV co-infection was 13.85% (113/816). Results from multivariate logistic regression analyses showed that age (25-45), family history of HBV and history of HepB vaccination were independent influencing factors for HBV and HIV coinfection, with OR (95%CI) as 1.738 (1.031-2.931), 2.898 (1.678-5.005) and 1.744 (1.052-2.892), respectively. Conclusion: The prevalence of HBV among HIV/AIDS patients was significantly higher than that in general population. HIV/AIDS patients aged between 25 and 45 and with family history of HBV were more likely to be infected with HBV, while HepB vaccination was associated with the reduction of HIV/HBV coinfection. Specific comprehensive prevention and treatment programs on HIV/AIDS patients need to be set up.目的： 了解HIV感染者HBV合并感染现状，并探讨该人群合并HBV感染的相关因素。 方法： 采用横断面研究方法，选取广西壮族自治区CDC及宁明县CDC的艾滋病门诊作为研究现场，招募研究对象纳入标准为年龄≥18周岁并确诊为HIV感染者，面对面问卷调查内容包括：一般人口学特征、吸毒史、性行为、乙型肝炎感染史等合并感染可能相关的因素。采集血样检测HBsAg。采用EpiData 3.0和SAS 9.4软件进行统计学分析，运用非条件logistic回归分析HIV/HBV合并感染的相关因素。 结果： HIV感染者合并感染HBV检出率为13.85%（113/816）。多因素非条件logistic回归分析结果显示，HIV感染者合并感染HBV的危险因素包括年龄（25~45岁者比≥45岁者，OR=1.738，95%CI：1.031~2.931）、HBV感染家族史（有HBV感染家族史者比无HBV感染家族史者，OR=2.898，95%CI：1.678~5.005）；无乙型肝炎疫苗接种史（无乙型肝炎疫苗接种史者比乙型肝炎疫苗接种史者，OR=1.744，95%CI：1.052~2.892）。 结论： HIV感染者合并感染HBV检出率较高。25~45岁、有HBV家族史者、无乙型肝炎疫苗接种史者的合并感染风险较高。建议针对HIV感染者加强HBV感染监测，控制合并感染。." @default.
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- W2982201110 date "2017-12-10" @default.
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- W2982201110 title "[Prevalence and related factors of HIV/HBV coinfection among HIV/AIDS patients]." @default.
- W2982201110 doi "https://doi.org/10.3760/cma.j.issn.0254-6450.2017.12.008" @default.
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