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- W2982220453 abstract "The purpose of the present study is to identify preoperative risk factors related to pulmonary complications with a focus on tumor-related factors. The authors conducted a retrospective review of the clinical records of all patients operated at the thoracic department of the Lviv State Oncological Regional Treatment and Diagnostic Center in 2010-2011. Tumor-related factors (histological type of lung cancer, tumor localization, TNM classification, past medical history of different cancer types) were analyzed. Postoperative pulmonary morbidity was defined as: respiratory failure, atelectasis, air leak more than 7 days, prolonged intubation (>72hours), pleural effusion, pleural empyema, chylothorax, and pneumothorax. The study included patients meeting the following criteria: age under 70, absence of neoadjuvant chemo- and/or radiotherapy, benign lung lesions, lung metastases, and non-curative lung resection. Logistic regression was performed using IBM SPSS Statistics 22 program. The result was considered statistically significant when p<0.05. 144 patients underwent surgery for primary lung cancer at our institution. Lobectomy was performed in 36.1%, pneumonectomy – in 59%, lung resection – in 4.9% of patients. Histological examination showed that 84 patients had squamous cell carcinoma, 31 patients – adenocarcinoma, 6 patients – large cell carcinoma, 6 patients – small cell carcinoma, 8 patients – NET and 9 patients – other histological types. 12 (8.3%) patients had a medical history of a different type of cancer. The 30-day postoperative mortality rate was 3.47%, postoperative morbidity was 36.8%. The analysis showed that presence of a different type of cancer in past medical history (p<0.05) remained a significant risk factor for respiratory morbidity after lung cancer surgery while the presence of NET reduces the risk of postoperative pulmonary complications (p<0.05). Presence of a different type of cancer in past medical history constitutes a significant risk factor for respiratory postoperative morbidity in lung cancer patients. Patients with NET have a lower risk of postoperative pulmonary complications. We suggest that this result requires confirmation by further research." @default.
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- W2982220453 date "2019-10-01" @default.
- W2982220453 modified "2023-10-18" @default.
- W2982220453 title "EP1.18-04 Do Tumor-Related Factors Predict Postoperative Pulmonary Complications in Patients Undergoing Curative Surgery for Lung Cancer?" @default.
- W2982220453 doi "https://doi.org/10.1016/j.jtho.2019.08.2449" @default.
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