Matches in SemOpenAlex for { <https://semopenalex.org/work/W2982255087> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2982255087 endingPage "74" @default.
- W2982255087 startingPage "74" @default.
- W2982255087 abstract "TPS 621: Exposure to metals, Johan Friso Foyer, Floor 1, August 26, 2019, 3:00 PM - 4:30 PM Background/Aim: Cigarette smoking is a major source of human exposure to cadmium (Cd), a known human lung carcinogen (IARC Group 1). In addition to smoking, certain occupations may serve as a source of substantial Cd exposure because Cd is also an environmental and industrial pollutant. Such additional exposures to this known carcinogen could be an important contributing factor to the inter-individual variation in lung cancer risk among smokers. We investigated the relationship between occupation and urinary Cd levels in 1,977 smokers from five race/ethnicity groups. Methods: Urinary Cd was measured by inductively coupled plasma mass spectrometry. Internal smoking dose was estimated by the biomarker urinary total nicotine equivalents (TNE). Occupation was measured by grouping participants based on their response to questions regarding longest history of industry and occupational categories. Urinary Cd was modeled using a log-normal distribution and censored linear regression, adjusting for age, gender, creatinine, education, TNE and smoking duration. Results: Urinary Cd levels varied substantially, ranging from below the limit of quantification to 6.0 ng/mL, with an adjusted geometric mean (GM) of 0.81 ng/mL (95% CI: 0.79, 0.84) for all smokers. Ethnic-specific analysis showed higher adjusted GM urinary Cd levels in Latino Americans (0.86 ng/mL), Native Hawaiians (0.84 ng/mL), Japanese Americans (0.81 ng/mL) and African Americans (0.81 ng/mL) as compared to Whites (0.74 ng/mL; p<0.05). Moreover, results showed that workers in occupations known to pose a risk for Cd exposure (e.g. mining, quarrying, and metal production or processing) had 11.4% (95% CI: 0.1%, 24.1%) higher levels of urinary Cd as compared to workers not likely to be exposed to Cd in the workplace, even after accounting for internal smoking dose and duration. Conclusions: Findings suggest that occupation may be an important factor contributing to Cd burden and may contribute to the differences in lung cancer risk among smokers." @default.
- W2982255087 created "2019-11-01" @default.
- W2982255087 creator A5050384161 @default.
- W2982255087 creator A5053024511 @default.
- W2982255087 creator A5074667922 @default.
- W2982255087 creator A5086160089 @default.
- W2982255087 date "2019-10-01" @default.
- W2982255087 modified "2023-09-24" @default.
- W2982255087 title "Variation in levels of urinary cadmium and its relationship with occupation in smokers from the Multiethnic Cohort Study" @default.
- W2982255087 doi "https://doi.org/10.1097/01.ee9.0000606484.30267.b5" @default.
- W2982255087 hasPublicationYear "2019" @default.
- W2982255087 type Work @default.
- W2982255087 sameAs 2982255087 @default.
- W2982255087 citedByCount "0" @default.
- W2982255087 crossrefType "journal-article" @default.
- W2982255087 hasAuthorship W2982255087A5050384161 @default.
- W2982255087 hasAuthorship W2982255087A5053024511 @default.
- W2982255087 hasAuthorship W2982255087A5074667922 @default.
- W2982255087 hasAuthorship W2982255087A5086160089 @default.
- W2982255087 hasBestOaLocation W29822550871 @default.
- W2982255087 hasConcept C126322002 @default.
- W2982255087 hasConcept C144024400 @default.
- W2982255087 hasConcept C149923435 @default.
- W2982255087 hasConcept C178790620 @default.
- W2982255087 hasConcept C185592680 @default.
- W2982255087 hasConcept C201903717 @default.
- W2982255087 hasConcept C2776256026 @default.
- W2982255087 hasConcept C2776319443 @default.
- W2982255087 hasConcept C2779547902 @default.
- W2982255087 hasConcept C2780306776 @default.
- W2982255087 hasConcept C2781197716 @default.
- W2982255087 hasConcept C42407357 @default.
- W2982255087 hasConcept C544657597 @default.
- W2982255087 hasConcept C55493867 @default.
- W2982255087 hasConcept C71924100 @default.
- W2982255087 hasConcept C72563966 @default.
- W2982255087 hasConcept C77411442 @default.
- W2982255087 hasConceptScore W2982255087C126322002 @default.
- W2982255087 hasConceptScore W2982255087C144024400 @default.
- W2982255087 hasConceptScore W2982255087C149923435 @default.
- W2982255087 hasConceptScore W2982255087C178790620 @default.
- W2982255087 hasConceptScore W2982255087C185592680 @default.
- W2982255087 hasConceptScore W2982255087C201903717 @default.
- W2982255087 hasConceptScore W2982255087C2776256026 @default.
- W2982255087 hasConceptScore W2982255087C2776319443 @default.
- W2982255087 hasConceptScore W2982255087C2779547902 @default.
- W2982255087 hasConceptScore W2982255087C2780306776 @default.
- W2982255087 hasConceptScore W2982255087C2781197716 @default.
- W2982255087 hasConceptScore W2982255087C42407357 @default.
- W2982255087 hasConceptScore W2982255087C544657597 @default.
- W2982255087 hasConceptScore W2982255087C55493867 @default.
- W2982255087 hasConceptScore W2982255087C71924100 @default.
- W2982255087 hasConceptScore W2982255087C72563966 @default.
- W2982255087 hasConceptScore W2982255087C77411442 @default.
- W2982255087 hasLocation W29822550871 @default.
- W2982255087 hasLocation W29822550872 @default.
- W2982255087 hasOpenAccess W2982255087 @default.
- W2982255087 hasPrimaryLocation W29822550871 @default.
- W2982255087 hasRelatedWork W1966632018 @default.
- W2982255087 hasRelatedWork W1982457890 @default.
- W2982255087 hasRelatedWork W2013461238 @default.
- W2982255087 hasRelatedWork W2037951921 @default.
- W2982255087 hasRelatedWork W2067970384 @default.
- W2982255087 hasRelatedWork W2084991106 @default.
- W2982255087 hasRelatedWork W2140506053 @default.
- W2982255087 hasRelatedWork W2274808664 @default.
- W2982255087 hasRelatedWork W2415738552 @default.
- W2982255087 hasRelatedWork W3090033145 @default.
- W2982255087 hasVolume "3" @default.
- W2982255087 isParatext "false" @default.
- W2982255087 isRetracted "false" @default.
- W2982255087 magId "2982255087" @default.
- W2982255087 workType "article" @default.