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• W2982396804 abstract "Background Hepatitis B viral infection represents a major public health problem worldwide. Despite being considered a vaccine- preventable disease; prevalence is still high in many regions. Most people are unaware that they are infected, and are frequently diagnosed during routine screening or as a work-up of advanced hepatic disease. The current study aimed to evaluate the proportion of the population currently infected, with past infection, or non-infected, and to determine the proportion of the population that is immunized. Methods A retrospective descriptive study was done, reviewing the serological markers for hepatitis B requested among the population who attended the MNGHA, Jeddah. Data from people screened between 2016 and 2018 were included in this study. Serological markers for hepatitis B included hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBcAbs), and hepatitis B surface antibodies (HBsAbs). Results Among 8370 people screened for hepatitis B, 312 (3.72%) individuals were found to be infected with hepatitis B (HBsAg/HBcAb positive, or at least HBsAg positive). The majority (92.34%, n=7729) was not infected (HBsAg negative/HBcAb negative, or HBsAg negative/HBcAb positive/HBsAb positive as past infection, and HBcAb negative/HBsAb positive as immune). Serological status of infection of the remaining 3.93% was unknown (only HBsAb negative tested, or isolated core: HBcAb positive/HBsAg negative/HBsAb negative [possible occult infection], or only HBcAb positive tested). Among subjects screened for HBsAbs (n=5619), 3382 (60.19%) were immune (HBsAb >10 IU/mL). Of 4960 individuals tested for HBcAbs, 862 (17.38%) were found to be positive, exposed to hepatitis B virus (active, occult, or past infection). The majority of infected individuals were Saudi (94.6%) and 57.6% were male; however, 75% of the population screened were Saudi, with 4.66% of infection among Saudis. Regarding the population exposed to hepatitis B (HBcAbs positive tested), 22.28% were Saudis, 20.08% from the Philippines, 16.90% from Pakistan, 14.52% from Egypt, and 9.55% from India, from the most frequently exposed nationalities. Among immune people, 54.3% were Saudi and 58.5% were female. Conclusion Despite the available vaccination for hepatitis B virus, more than 3% of the population screened was infected, and more than 17% had been exposed to the virus (HBcAbs positive). Screening for hepatitis B virus, early identification of infected individuals, and vaccination for the non-immune population must be encouraged." @default.
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• W2982396804 date "2019-04-01" @default.
• W2982396804 modified "2023-09-25" @default.
• W2982396804 title "32 Hepatitis B serological status among a population screened in the ministry of national guard health affairs in saudi arabia between 2016 and 2018" @default.
• W2982396804 doi "https://doi.org/10.1136/bmjoq-2019-psf.32" @default.
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