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• W2982426677 endingPage "755" @default.
• W2982426677 startingPage "700" @default.
• W2982426677 abstract "Abstract Higher plants produce divergent classes of specialized (so called secondary) metabolites, such as alkaloids, phenolics, terpenoids, and so on. Among them, alkaloids, which contain nitrogen atom often in heterocyclic ring, are most biologically active and used as poisons and/or also pharmaceuticals. Whereas natural resources are commonly used for the preparation for these chemicals, shortage of natural resources in quantity and quality need more advanced technology for the production. Recent progresses in biochemistry, molecular biology and recombinant technology provide new way for the production of specialized metabolites without chemical synthesis. Metabolic engineering in target plants and reconstruction of biosynthetic pathway in heterologous hosts, especially microbes using synthetic biology, offers great potentials to improve the productivity and quality of these metabolites. In this report, recent progresses in the isolation and identification of molecular tools for metabolic engineering and synthetic biology are critically summarized and also some achievement of alkaloid engineering in benzylisoquinoline alkaloids (BIAs) such as berberine, morphine, noscapine and sanguinarine, monoterpenoid indole alkaloids (MIAs) such as vinca alkaloids, nicotine and tropane alkaloids, steroidal glycoalkaloids such as solanine and so on are summerized." @default.
• W2982426677 created "2019-11-08" @default.
• W2982426677 creator A5031484098 @default.
• W2982426677 date "2020-01-01" @default.
• W2982426677 modified "2023-10-16" @default.
• W2982426677 title "Plant Alkaloid Engineering" @default.
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